نتایج جستجو برای: prostate antigen serum psa test
تعداد نتایج: 1338314 فیلتر نتایج به سال:
PURPOSE Several single nucleotide polymorphisms (SNP) have been associated with the risk of prostate cancer. The clinical utility of using SNPs in the early detection of prostate cancer has not been evaluated. EXPERIMENTAL DESIGN We examined a panel of 25 SNPs from candidate genes and chromosomal regions in 3,004 unselected men who were screened for prostate cancer using serum prostate-specif...
BACKGROUND The combined use of free and total prostate-specific antigen (PSA) in early detection of prostate cancer has been controversial. This article systematically evaluates the discriminating capacity of a large number of combination tests. METHODS Free and total PSA were analyzed in stored serum samples taken prior to diagnosis in 429 cases and 1,640 controls from the Physicians' Health...
Prostate gland is an accessory of the male reproductive system.Prostate begins development from mesenchymal tissue, surrounding urogenital sinus in 3 rd month gestation. Epithelial buds invaginate posterior on either side verumontanum. Concurrently, Wolffian ducts develop into seminal vesicles, epididymis, Vasdeferens and ejaculatory that are stimulated by fetal testosterone. Histologically all...
To the Editor: Prostate-specific antigen (PSA) is a protein produced almost exclusively by the prostate. Although various tissues in females have been found to produce very small amounts of PSA, serum PSA levels in females are quite low and are measurable only with ultrasensitive PSA immunoassays. In a study of 1064 women, the highest serum PSA levels were less than 1 μg per liter, and only 1.5...
Theobservational study by BentmarHolgersson and colleagues (1) of a cohort of 40to 79-year-old Caucasian men from the EuropeanMale Ageing Study, without prostate cancer at baseline, demonstrated that the 16% of subjects carrying the A-allele androgen receptor (AR) polymorphism compared with the 84% of subjects carrying theG-allele AR polymorphism exhibited a nearly 2-fold risk of having a serum...
Introduction: Benign Hyperplasia of the Prostate (BHP) and prostate cancer comprise about 90% all diseases gland. An increase in serum Specific Antigen (PSA) is an indicator underlying hyperplasia, inflammation, or cancer. Mast cells are found both inflamed tumour tissue. Aim: To find correlation mast cell count with age, weight prostate, PSA level, thereby distinguishing between benign inflamm...
We compared the ability to diagnose skeletal metastasis between serum prostate specific antigen (PSA), C-terminal propeptide of blood type I procollagen (PICP), and urine type I collagen-crosslinked N telopeptide (NTx) in prostate cancer patients. In sixty-nine patients with prostate cancer, bone scintigraphy was performed, and serum PSA and PICP and urine NTx were measured. The median level of...
Objective To test the diagnostic performance of percent free prostate-specific antigen (%fPSA) in predicting any prostate cancer (PCa) and high-grade prostate cancer (HGPCa) in a retrospective multi-center biopsy cohort with a PSA level of 4.0-10.0 ng/mL in China. Methods Consecutive patients with a PSA of 4.0-10.0 ng/mL who underwent transrectal ultrasound-guided biopsy were enrolled at 16 C...
Prostate cancer is the second leading cause of cancer deaths in men in the United States. Use of the serum prostate specific antigen (PSA) test to screen men for prostate cancer since the late 1980s has improved the early detection of prostate cancer, however low specificity of the test translates to numerous false positive results and many unnecessary biopsies. New biomarkers to aid in prostat...
PURPOSE This study was conducted to identify the predictive factors for prostate cancer in patients with prostate-specific antigen (PSA) levels equal to or less than 4 ng/ml. MATERIALS AND METHODS A retrospective study of medical records was conducted on 292 patients with initial serum PSA ≤4 ng/ml among 2,305 patients who underwent prostate biopsy from January 2003 to December 2008. Prostate...
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