نتایج جستجو برای: protein interaction network could reveal
تعداد نتایج: 3036235 فیلتر نتایج به سال:
Embryonic stem cells were isolated from the mouse in 1981. Two landmark papers (Evans & Kaufman, 1981; Martin, 1981) described the isolation from the blastocyst of a cell line, that grew rapidly, was maintained by passaging, had a normal karyotype unlike embryonal carcinoma cells and could be induced to differentiate into a wide variety of cell types by injecting them into the mouse or by cultu...
Introduction: Obsessive-Compulsive Disorder (OCD) as one of the important mental problems is valuable topic for proteomic research studies to better understand the underlying mechanisms of this disorder. Methods: In this paper, gel-based proteomic was used to investigate the proteome profile of 16 female patients with OCD, washing subtype before and after treatment with fluoxetine and co...
A Bayesian network has often been modeled to infer a gene regulatory network from expression data. Genotypes along with gene expression can further reveal the regulatory relations and genetic architectures. Biological knowledge can also be incorporated to improve the reconstruction of a gene network. In this work, we propose a Bayesian framework to jointly infer a gene network and weights of pr...
Protein interaction networks have become a tool to study biological processes, either for predicting molecular functions or for designing proper new drugs to regulate the main biological interactions. Furthermore, such networks are known to be organized in sub-networks of proteins contributing to the same cellular function. However, the protein function prediction is not accurate and each prote...
Protein-protein interaction is one of the crucial ways to decipher the functions of proteins and to understand their role in complex pathways at cellular level. Such a protein-protein interaction network in many crop plants remains poorly defined owing largely to the involvement of high costs, requirement for state of the art laboratory, time and labour intensive techniques. Here, we employed c...
Angiogenesis involves stimulation of endothelial cells (EC) by various cytokines and growth factors, but the signaling mechanisms are not completely understood. Combining dynamic gene expression time-course data for stimulated EC with protein-protein interactions associated with angiogenesis (the "angiome") could reveal how different stimuli result in different patterns of network activation an...
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