BACKGROUND Psoriasis is associated with a form of spondyloarthropathy in 10-30% of cases. A major feature of psoriatic arthritis is enthesitis. In some patients with psoriasis the presence of enthesitis could be underdiagnosed. OBJECTIVE To investigate the presence of lower limbs entheseal abnormalities in patients with chronic plaque psoriasis without signs and symptoms of psoriatic arthriti...

Psoriasis is associated with being overweight, but the temporal relationship is not known. This historical cohort study tested whether severe psoriasis resulting in hospitalization in adulthood was preceded by excess increase in age-adjusted body mass index, a known risk factor in childhood for being overweight in adulthood. The study cohort was based on the Copenhagen School Health Records Reg...

Background. Psoriasis is a chronic skin disorder that impairs patients health-related quality of life. It associated with need in specialized medical care and essential costs. may be the reason for temporary or permanent disability. Patient registries are important sources epidemiological clinical data on psoriasis provided.
 Aims. To describe demographic characteristics, characteristics d...

OBJECTIVES To compare narrowband UV-B (TL-01 lamp) phototherapy for psoriasis with individual patient starting doses based on minimal erythemal dose (MED) determination vs a standard fixed starting dose and to compare the efficacy of 70% of MED vs 50% of MED starting dose regimens. DESIGN Single-center, randomized, double-blind, clinical trial. SETTING Department of Dermatology, Ninewells H...

objective: psoriasis is a chronic inflammatory disease. it may cause poor quality of life. the purpose of this study was to determine the prevalence of insulin resistance in patients with psoriasis to clarify the relationship between insulin resistance and psoriasis. materials and methods: this case-control study was conducted on 110 patients with psoriasis and 110 healthy people. fasting serum...

INTRODUCTION: Plaque-type psoriasis affecting the nails, scalp, hands or feet can often be difficult to treat; for example, topical treatments and phototherapy may not penetrate the nail plate or scalp. The objective of this large, international, multicentre study was to investigate the efficacy of efalizumab in a Latin American population of adult patients with moderate-to-severe chronic plaqu...

Psoriasis is an autoimmune and recurrent chronic inflammatory skin disease. About 1-3% of the world wide populations are affected. The characteristic features are hyperprolifration of keratinocytes leading to redness, thickening and scaling of epidermis followed with itching and appearance of the lesions which in most cases bother the patients medically and psychologically. Psoriasis is symptom...

Psoriasis is a common inflammatory skin disease characterized by the appearance of red scaly plaques that can affect any part of the body. High prevalence, chronicity, disfiguration, disability, and associated comorbidity make it a challenge for clinicians of multiple specialties. Likewise, its complex pathogenesis, comprising inflammation, hyperproliferation, and angioneogenesis, intrigues num...

BACKGROUND Plaque-type psoriasis produces significant morbidity, has negative effects on patients' health-related quality of life (HRQoL), and represents an economic burden. OBJECTIVES The assessment of disease severity, HRQoL and health care in plaque-type psoriasis in everyday German medical practice. METHODS Details of patients with plaque-type psoriasis were recorded by 48 dermatologist...

Psoriasis is a common chronic skin disorder characterized by abnormal epidermal proliferation and infiltration of inflammatory cells which affects approximately 2-4 % of the general population [1-3]. Psoriasis Vulgaris (PV), the most common clinical variant, comprises 85 to 90% of all patients with psoriasis. This disease is usually manifested as well-demarcated erythematous oval plaques with s...