This review addresses the importance of psychoneuroimmunology (PNI) studies in understanding the role of acute and chronic psychological stressors on the immune system and development of coronary artery disease (CAD). Firstly, it illustrates how psychological stressors change endothelial function and lead to chemotaxis. Secondly, acute psychological stressors lead to leukocytosis, increased nat...

Over the past few decades, the inextricable link between the endocrine, immune and nervous systems formed the basis of a new field, dubbed psychoneuroimmunology. In this paradigm, one system is subject to the vicissitudes of the other through several intricate feedback loops, such that conditions affecting the one have farreaching effects on the other. As such, critical illness (especially seps...

OBJECTIVE Provide an orientation to psychoneuroimmunology, a rationale for including assessments of immune function in intervention studies of pediatric chronic illness, review the current literature, and provide recommendations for future research. METHODS Using electronic searches and previous reviews, selected and reviewed published studies in which immunological changes related to psychol...

Discovery Medicine, Volume 5, Number 26, Pages 165-169, April 2005 There is an extensive body of scientific literature related to the field of research called psychoneuroimmunology. Clinical studies, backed up by mechanism studies, have provided convincing evidence that the central nervous system (CNS) interacts with the endocrine and immune systems and that these interactions are bi-directiona...

OBJECTIVE Many allergy patients complain of fatigue, moodiness, and dysphoria during their allergy seasons. This study evaluated the effect of symptomatic allergic rhinitis on both fatigue level and mood. METHOD Symptomatic ragweed allergic rhinitis patients on no medications and healthy control subjects completed the Multi-Dimensional Fatigue Inventory and the Positive Affect-Negative Affect...

psychosocial interventions can affect the immune system and the progression of medical disorders. Investigators have begun to establish that responses to specific stress situations can result in impaired immunity and that relaxation and cognitive-behavioral stress management have health benefits, so efforts in helping persons maintain the highest level of health possible have become even more i...

People who have experienced traumatic events have higher rates than the general population of a wide range of serious and life-threatening illnesses including cardiovascular disease, diabetes, gastrointestinal disorders, and cancer. An important question, for both researchers and clinicians, is why this occurs. Researchers have discovered that traumatic events dysregulate the hypothalamic-pitui...

In recent decades, many studies have been developed in psychoneuroimmunology that associate stress, arising from multiple different sources and situations, to changes the immune system, medical or immunological point of view as well biochemical one. this paper, we identify important behaviors interplay between system stress seek represent them qualitatively a paradigmatic, yet simple, mathemati...