نتایج جستجو برای: ptld post

تعداد نتایج: 404553  

Journal: :Transplant international : official journal of the European Society for Organ Transplantation 2012
Isabelle Binet

The main risk is the subsequent development of EBVrelated post-transplant lymphoproliferative disorder (PTLD). This association is well known but was recently re-examined by the Registry of Transplant Recipients in the United States. The analysis confirmed the higher risk of PTLD for D+/R) with adjusted hazard ratios up to 3.58 for kidney transplants [2]. In transplantation settings the lytic r...

2008
Mitsugi Shimoda Junji Kita Masato Kato Tokihiko Sawada Keiichi Kubota

Lymphoproliferative disorders following liver transplantation are often Epstein-Barr virus (EBV)-related highgrade B cell lymphomas. EBV-negative and low-grade lymphoma is a very rare condition after cadaveric as well as living donor liver transplantation (LDLT). Herein we report a case of follicular lymphoma with negative EBV viral capsid antigen (VCA), IgM, IgG and Epstein-Barr virus-encoded ...

Journal: :Blood 2007
Lindsay M Morton Ola Landgren Nilanjan Chatterjee David Castenson Ruth Parsons Robert N Hoover Eric A Engels

Posttransplantation lymphoproliferative disorder (PTLD) is a serious complication of solid organ transplantation. Hepatitis C virus (HCV) infection has been linked to increased risk of lymphoma among immunocompetent individuals. We therefore investigated the association between HCV infection and PTLD in a retrospective cohort study of all individuals in the United States who received their firs...

2015
Xiaofan Li Nainong Li Ting Yang Zhizhe Chen Jianda Hu

Ultra early posttransplantation lymphoproliferative disorder (PTLD) is a rare and fatal complication after hematopoietic stem cell transplantation (HSCT). Here we report, by lymph node (LN) flowcytometry, that we early recognized ultra early PTLD after an HLA-matched sibling allo-HSCT followed by a successful treatment with anti-CD20 antibody (rituximab) in a patient in progress disease for ang...

2016
Maryam Rahbar Gholamreza Poormand Masoud Karkhaneh Mahmoodi Aboozar Jazayeri Seyed Mohammad Jazayeri

Epstein-Barr virus (EBV) is associated with a wide range of malignancies and complications like post-transplant lymphoproliferative disorder (PTLD). To suppress active EBV infection in transplant recipients, who are at a heightened risk of developing PTLD, EBV DNAemia monitoring has been recommended. Quantitative multiplex real time polymerase chain reaction (QMRTPCR) offered the advantage of d...

Journal: :Blood 1999
R E Curtis L B Travis P A Rowlings G Socié D W Kingma P M Banks E S Jaffe G E Sale M M Horowitz R P Witherspoon D A Shriner D J Weisdorf H J Kolb K M Sullivan K A Sobocinski R P Gale R N Hoover J F Fraumeni H J Deeg

We evaluated 18,014 patients who underwent allogeneic bone marrow transplantation (BMT) at 235 centers worldwide to examine the incidence of and risk factors for posttransplant lymphoproliferative disorders (PTLD). PTLD developed in 78 recipients, with 64 cases occurring less than 1 year after transplantation. The cumulative incidence of PTLD was 1.0% +/- 0.3% at 10 years. Incidence was highest...

Journal: :Blood 2002
Pierluigi Porcu Charles F Eisenbeis Ronald P Pelletier Elizabeth A Davies Robert A Baiocchi Sameek Roychowdhury Srinivas Vourganti Gerard J Nuovo William L Marsh Amy K Ferketich Mitchell L Henry Ronald M Ferguson Michael A Caligiuri

Posttransplantation lymphoproliferative disorder (PTLD) is a life-threatening Epstein-Barr virus (EBV)-associated B-cell malignancy occurring in 1% to 2% of renal transplantation patients. Host- and PTLD-related factors determining the likelihood of tumor response following reduction of immune suppression (IS) and antiviral therapy remain largely unknown. Standard therapy for PTLD is not well e...

2014
Stefanie Linnerbauer Uta Behrends Dinesh Adhikary Klaus Witter Georg W. Bornkamm Josef Mautner

Polyclonal Epstein-Barr virus (EBV)-infected B cell line (lymphoblastoid cell lines; LCL)-stimulated T-cell preparations have been successfully used to treat EBV-positive post-transplant lymphoproliferative disorders (PTLD) in transplant recipients, but function and specificity of the CD4+ component are still poorly defined. Here, we assessed the tumor-protective potential of different CD4+ T-c...

2015
Yun-Wen Chen Hun-Ju Yu Yi-Chieh Poon Hsi-Kung Kuo

We report a case of an iris tumor with muttonfat keratic precipitates in a young patient after liver transplantation surgery. A 6yearold girl underwent liver transplantation for congenital biliary atresia and was subsequently immunosuppressed with oral cyclosporine. We examined her 5 years after transplantation because of a "white nodule in her left eye," which had been detected by her father o...

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