Radiotherapy is one of important approaches for pulmonary adenocarcinoma. However, many studies have shown that radiation can also enhance the ability of tumor cells metastasis, although the lung adenocarcinoma could be killed. The increased metastasis induced by radiation is associated with the activation of STAT3 in lung adenocarcinoma cells. Based on the importance role of STAT3 in cell prol...

To investigate the performance of combined 18F-FDG Positron Emission Tomography/Computed Tomography with high-resolution CT for differentiating invasive adenocarcinoma from adenocarcinoma in situ (pre-invasive lesion) or minimally invasive adenocarcinoma in stage IA lung cancer patients with solitary ground-glass opacity nodules. This retrospective study enrolled 58 consecutive stage IA pulmona...

There have been several epidemiological studies of the association between 25-hydroxyvitamin D (25(OH)D) level and lung cancer risk. We explored the potential association between serum 25(OH)D levels and mutations in epidermal growth factor receptor (EGFR) in patients with pulmonary adenocarcinoma. We analyzed clinical data from 135 patients whose serum 25(OH)D levels were measured and EGFR mut...

In stroke patients, upper extremity deep vein thrombosis (UEDVT) is uncommon compared with lower extremity. Unlike the blood stasis in extremity, UEDVT has been developed by secondary cause. We reported a case of patient repeated UEDVT, presenting superficial venous congestion, who was finally diagnosed pulmonary adenocarcinoma. The cause non-bacterial thromboembolism formed at mitral valve. Ou...

Metastasis of unknown primary site in serous pleural effusion is common and cytopathological analysis may have important therapeutic implications. Primary lung and metastatic tumors may share similar cytopathological features with difficulties in differential diagnosis especially in routine cytology practice. TTF-1 is highly specific and sensitive in the diagnosis of certain types of primary lu...