Emphasis has shifted from the "doomed" organ concept of an exposed pulp to one of hope and recovery. The era of vital-pulp therapy has been greatly enhanced with the introduction of various pulp capping materials. The aim of this article is to summarize and discuss about the various and newer pulp capping materials used for protection of the dentin-pulp complex.

Water is indispensable and one of the precious natural resource of this planet. Ground water is an important source of water supply throughout the world. Fluoride poisoning arises from drinking fluoride rich ground water. Our present experiment was designed to study the efficacy of NaF on the splenocytes and its role in immunogenic response. The albino rats were taken for the experiment and ran...

BACKGROUND Successful pulp regeneration depends on identification of pulp stem cells capable of differentiation under odontoblastic lineage and producing pulp-dentinal like structure. Recent studies demonstrate that platelet-derived growth factor (PDGF) plays an important role in damage repair and tissue regeneration. The aim of this study was to identify a subpopulation of dental pulp cells re...

Pain caused by acute pulpitis (AP) is a common symptom in clinical settings. However, its underlying mechanisms have largely remained unknown. Using AP model, we demonstrated that dental injury caused severe pulp inflammation with up-regulated serum IL-1β. Assessment from head-withdrawal reflex thresholds (HWTs) and open-field test demonstrated nociceptive response at 1 day post injury. A consi...

Active germinal centers are recognized as areas of rapidly proliferating blast cells in the white pulp of the spleen and in the cortex of lymph nodes. The origin and life history of these cells, their relationship to the surrounding mantle zone of small lymphocytes and, in particular, the functional significance of these two groups of cells is still unknown. Flemming (1) has proposed that germi...

This study evaluated the human pulp tissue response following direct capping with Clearfil Protect Bond (CPB) self-etching adhesive containing an antibacterial monomer MDPB. The pulps of third molar teeth were exposed by removal carious tissue. In experimental group, CPB was applied to and dentin. control groups, SE (CSE) or calcium hydroxide-based cement (CH) surfaces. All filled resin composi...

Captive and wild African elephants frequently suffer tusk fractures. Several institutions shorten the tusks of captive elephants to reduce fractures and injury as a result of behaviour within enclosures. Fracturing or coronal amputations that expose pulp lead to pain for the elephant. Estimating coronal pulp lengths may thus help to minimise the risk of pulp exposure during amputations. We aime...

Regeneration of dental pulp after pulpectomy was accomplished recently by autologous transplantation of dental pulp stem/ progenitor cells into the root canal. The identical patterns of qualitative and quantitative protein and mRNA expression in the regenerated pulp and normal pulp demonstrated complete pulp regeneration. The lack of tissue specific markers in the dental pulp is a major challen...

Vital Pulp Protection and Therapy (VPPT) is the treatment that maintains pulp tissue in a healthy and functional state, whenever the dentin-pulp complex has been compromised by caries, trauma or restorative procedures. Pulp vitality and function is not essential for mature tooth survival. Mature permanent teeth without a vital pulp can survive for a long time after a successful endodontic treat...