Chrysiasis is the phenomenon of bluish to slategray skin pigmentation induced by prolonged treatment with gold salts. The most common etiology is the administration of gold salts to patients with rheumatoid arthritis. Although parental gold salt administration is now uncommon because of the availability of biologic agents and disease-modifying antirheumatic drugs, chrysiasis may still be seen b...

Port wine stains (PWS) are the most common vascular malformation of the skin, occurring in 0.3% to 0.5% of the population. Noninvasive laser irradiation with flashlamp-pumped pulsed dye lasers (selective photothermolysis) currently comprises the gold standard treatment of PWS; however, the majority of PWS fail to clear completely after selective photothermolysis. In this review, the clinically ...

Rosacea is a chronic and progressive inflammatory skin disorder affecting the facial convexities for which no curative measure is currently available. Forty consecutive patients with rosacea were treated with the Cynosure PhotoGenica V pulsed dye laser. The improvement following laser therapy was assessed according to a sliding scale: 1 (worse after treatment), 2 (no improvement), 3 (slight imp...

Laser has proven to be an effective and safe method of treating ureteral stones. When the electromagnetic energy of a laser pulse is selectively absorbed by stone, a plasma fonns at the surface. This plasma, which is composed of ions and electrons, continues to absorb laser energy reaching very high pressure and generating a shock wave that fragment the stone. The degree of stone fragmentation ...

Port wine stain of Sturge-Weber syndrome represents a cosmetic prejudice with social consequences. We have treated eight patients with a 585 nm pulsed dye laser. According to our experience, the treatment is not risky provided that adequate care is taken; the cosmetic result on the V1 port wine stain component is satisfactory.

We have developed a simplified version of the side-pumped pulsed dye laser which has a spectral halfwidth of 1.25 GHz and a peak power of 10 kW at 600 nm. The basic laser consists of only four components (output mirror, dye cell, diffraction grating, and tuning mirror) and is exceptionally easy to align. Since the beam expander has been eliminated, the laser cavity can be made quite compact. Un...

BACKGROUND To our knowledge, no systematic analysis of nonablative laser therapy has been performed. OBJECTIVE To alter the parameters (fluence, spot size, pulse duration, and use of cooling spray) for the pulsed dye laser to determine the precise settings that would yield the most favorable dermal remodeling in a porcine model. METHODS Research was conducted in an animal laboratory at Alba...

Granuloma faciale (GF) is a rare cutaneous disorder categorized as a localized form of small-vessel vasculitis. Clinically, it manifests as single or multiple well-demarcated red-brown plaques, papules and nodules, nearly always confined to the face. Herein, we report a 39-year-old man with multiple red-brown infiltrated plaques on face and extrafacial lesions on back, shoulders and both arms. ...

Background. Basal cell carcinoma (BCC) is the most prevalent skin cancer. Because of its highly vascular characteristic, it is amendable to treatment with pulse dye laser (PDL). The goal of this study is to determine the safety and efficacy of PDL therapy for mostly facial BCCs. Materials and Methods. Sixteen men and thirteen women (29 total) with 39 biopsy-proven BCCs were treated with 1-4 PDL...