objective(s): organic cation transporter 3 (oct3) as a high-capacity transporter contribute to the metabolism of metformin. the present study was conducted to determine the genotype frequencies of the variant oct3-1233g>a (rs2292334) in patients with newly diagnosed type 2 diabetes (t2d) and its relationship with response to metformin. materials and methods: this study included 150 patients wit...

the sorption and desorption behaviors of eu(iii) from aqueous solutions with cation exchange resins containing carboxyl groups (d155 resin) were studied in terms of varied eu(iii) concentration, adsorbent dosage, ph, contact time and temperature. batch shaking sorption experiments were carried out to evaluate the performance of d155 resin in the removal of eu(iii) from aqueous solutions. the lo...

abstract plant nonspecific lipid transfer proteins (nsltps) are divided into nsltp1 and nsltp2. the existence of an internal hydrophobic cavity, is a typical characteristic of nsltps that serves as the binding site for lipid substrates. in this communication a simple, rapid and low-cost alternative method was developed for purification of nsltp2 from rice paddy. after extracting, final supernat...

the mechanism by which bi-and trivalent cations affect human liver phosphatidatephosphohydrolase (pap) activity was investigated. bivalent cations up to 1 mm increased pap activity whereas at higher concentrations the activity of the enzyme decreased. the stimulatory concentration for trivalent cations such as al3+ and cr3+, however, was much lower being 2 m m and 1 m m, respectively. all catio...

in concentration of hydrogen peroxide, first, the solution should be quite pure, and then, it concentrate with methods such as vacuum distillation and cooling crystallization, because impurities in the hydrogen peroxide solution in high concentrations are causing decomposition of this substance; that is very dangerous. the purpose of this article is separation of chromium and magnesium cations ...

in this study, a multi-objective genetic algorithm (moga) is utilized to extract interpretable and compact fuzzy rule bases for modeling nonlinear multi-input multi-output (mimo) systems. in the process of non- linear system identi cation, structure selection, parameter estimation, model performance and model validation are important objectives. furthermore, se- curing low-level and high-level ...