Abstract Derivatives of formyl pyrazole were synthesized by the reaction acetophenone, 4-methyl 3-acetyl furan, thiophen and phenyl hydrazine derivatives. The product was treated with Vilsmeier reagent producing different derivatives which characterized FT-IR, 1HNMR, Elemental analysis Mass spectroscopy. reacted chitosan to produce chitosan/ Schiff base. These bases FT-IR TGA.The antimicrobial ...

Considerable efforts have been directed towards the discovery of selective cyclooxygenase isoxyme 1 (COX-1) inhibitors due to recent work highlighting involvement COX-1 in pathogenesis pain, neuroinflammation, cancer and cardiovascular disorders. In this context, paper aims describe 2-pyrazolines endowed with inhibitory potency. An efficient microwave-assisted synthetic method was applied for p...