The utility of hydrogen stable isotope ratio measurement by IR-MS for establishing the origin of ephedrine and pseudoephedrine (ephedrines), precursors of methamphetamine, was evaluated. There are two kinds of commercial semisynthetic ephedrines, one produced from molasses and the other from pyruvic acid. While the semisynthetic ephedrines derived from pyruvic acid cannot be discriminated from ...

Chronic exposure to polychlorinated biphenyls (PCBs), ubiquitous environmental contaminants, can adversely affect the development and function of the nervous system. Here we evaluated the effect of PCB exposure on mitochondrial function using the PCB mixture Aroclor-1254 (A1254) in SH-SY5Y neuroblastoma cells. A 6-hour exposure to A1254 (5 μg/ml) reduced cellular ATP production by 45%±7, and mi...

Of eight young men on high.fat diets (60% of caloric intake) for 42 days, four developed serum glutamic-pyruvic tra nsaminase concentrations greater than normal, while lactic dehydrogenase, glutamic-oxalacetic transaminase, and alkaline and acid phosphatases were within the normal range. Serum triglyceride levels were also within the normal range, but significant correlations between serum trig...

in this research, the effect of different storage conditions (cold, semi technical and traditional storages) at 180 days after storage on the qualitative and quantitive properties of garlic populations were investigated. white and pink populations were packaged in wooden boxes and net pockets and factors i. e. weight loss, moisture content, spoilage, firmness and total pyruvic acid were measure...

Hyperpolarized singlet order is available immediately after dissolution DNP, avoiding need for additional preparation steps. We demonstrate this procedure on a sample of [1,2-(13)C(2)]pyruvic acid.

Correspondence to: Dr D J Powrie, Academic Unit of Respiratory Medicine, Dominion House, St Bartholomew’s Hospital, London EC1A 7BE, UK; duncanpowrie@ hotmail.com . . . . . . . . . . . . . . . . . . . . . . . T he Winter Meeting of the BTS affords us the opportunity to catch up with friends and colleagues and to keep abreast of recent advances. Perhaps most importantly, it is also an ideal foru...

Sublethal toxicity of copper sulphate on carbohydrate metabolism was studied in selected tissues of freshwater mussel, Lamellidens marginalis. Levels of glycogen and pyruvic acid decreased while lactic acid showed an increase. Activities of LDH, SDH and MDH decreased while G-6-PDH activity increased. There appears to be a shift in the carbohydrate metabolism from aerobic to anaerobic type due t...

Urine cultures represent one of the most commonly submitted specimens to a microbiology laboratory. In an attempt to manage effectively this type of specimen, Bac-T-Screen (BTS), nitrate and leukoestrase test were performed on all clean catch urine specimens sent for culture. Three hundred and four specimens were screened by these methods. The BTS, by itself, had the highest sensitivity, and sp...