This paper analyzes the role of global land-use in determining potential greenhouse gas mitigation by land-based activities in agriculture and forestry. Land-based activities are responsible for over a third of global greenhouse gas emissions, yet the economics of land-use decisions have not been explicitly modeled in global mitigation studies. In this paper, we develop a new, general equilibri...

Huntington disease-like 2 (HDL2) and Huntington disease (HD) are adult-onset neurodegenerative diseases characterized by movement disorders, psychiatric disturbances and cognitive decline. Brain tissue from HD and HDL2 patients shows degeneration of the striatum and ubiquitinated inclusions immunoreactive for polyglutamine (polyQ) antibodies. Despite these similarities, the diseases result from...

Institutions formed through local collective action can provide effective solutions to environmental and resource problems. Rigorous quantitative analysis of these issues is often missing, however, and the groundwater economics literature fails to address the role of these types of institutions. This paper explores how the physical properties of the groundwater resource affect the incentives of...

Ritsche K, Smith J, Mellick P, Wideman L. Acute Exercise-Induced Growth Hormone is Attenuated in Response to Short-Term, HighIntensity Exercise Training. JEPonline 2014;17(6):1-12. The aim of this study was to determine if 3-wks of short-term, high-intensity exercise training (HIT) alters growth hormone (GH) release. Nineteen recreationally active males (Mean ± SD) (age = 24.9 ± 3.9 yrs, BF% = ...

BACKGROUND AND OBJECTIVES In acute leukemias, chromosomal translocations involving the 11q23 band are frequently, but not invariably, associated with MLL gene rearrangement and their finding is associated with a poor prognosis. We observed two new translocations with a breakpoint in the 11q23 region at standard cytogenetic analysis: a previously undescribed t(3;11)(q21;q23) in a 70-year old wom...

Nineteen benign [World Health Organization (WHO) grade I; MI], 21 atypical (WHO grade II; MII), and 19 anaplastic (WHO grade III; MIII) sporadic meningiomas were screened for chromosomal imbalances by comparative genomic hybridization (CGH). These data were supplemented by molecular genetic analyses of selected chromosomal regions and genes. With increasing malignancy grade, a marked accumulati...

Anaplastic lymphoma kinase (ALK)-positive diffuse large B cell lymphoma (DLBCL) with expression of CD38 and lack of CD30 was first described in 1997. With few exceptions these ALK-positive DLBCL show a fine granular cytoplasmic ALK-staining characteristic for the fusion of CLTC with ALK caused by the reciprocal translocation t(2;17)(p23;q23). This rare but characteristic lymphoma subtype is ass...

Uterine leiomyomata (UL), the most common neoplasm in reproductive-age women, are classified into distinct genetic subgroups based on recurrent chromosome abnormalities. To develop a molecular signature of UL with t(12;14)(q14-q15;q23-q24), we took advantage of the multiple UL arising as independent clonal lesions within a single uterus. We compared genome-wide expression levels of t(12;14) UL ...