abstract introduction:  this study was performed to compare the effects of low-dose interferon beta-1(cinnovex,30 mcg) and high-dose interferon beta-1(rebif,44 mcg) on the reduction of the number and size of plaques in magnetic resonance imaging (mri) in patients with multiple sclerosis (ms). methods and materials: this historical cohort study, which was performed in 2014 in sanandaj (western p...

The linear-quadratic (LQ) model is widely used to model the effect of total dose and dose per fraction in conventionally fractionated radiotherapy. Much of the data used to generate the model are obtained in vitro at doses well below those used in radiosurgery. Clinically, the LQ model often underestimates tumor control observed at radiosurgical doses. The underlying mechanisms implied by the L...

A method is proposed for using survival curve parameters for calculating the change in total dose necessary to achieve an equal response in a tissue when the dose per fraction is varied. The method uses the ratio alpha/beta of the coefficients of the linear quadratic survival formula and accounts only for the effect of repair of cellular injury. Absolute values for alpha and beta are not requir...

The paper is concerned with the bifurcation of limit cycles in general quadratic perturbations of a quadratic reversible and non-Hamiltonian system, whose period annulus is bounded by an elliptic separatrix related to a singularity at infinity in the poincar'{e} disk. Attention goes to the number of limit cycles produced by the period annulus under perturbations. By using the appropriate Picard...

Quadratic programming (QP) is an optimization problem wherein one minimizes (or maximizes) a quadratic function of a finite number of decision variable subject to a finite number of linear inequality and/ or equality constraints. In this paper, a quadratic programming problem (FFQP) is considered in which all cost coefficients, constraints coefficients, and right hand side are characterized by ...

aminul islam1*, jatish chandrabiswas 1, a. j. m. sirajul karim2, mst. salmapervin3, and md. abu saleque4 1*-soil science division, bangladesh rice research institute, gazipur-1701, bangladesh 2-department of soil science, bangabandhu sheikh mujibur rahman agricultural university, salna, gazipur-1706, bangladesh 3-plant physiology division, bangladesh rice research institute, gazipur-1701, bangl...

OBJECTIVE To compare the inverse planning optimization based on total dose constraints versus conventional treatment plan (point A planning method) for cervical carcinoma, and evaluate the benefit of CT-based image-guided brachytherapy. METHODS We prospectively analyzed data of 10 consecutive patients with cervical cancer treated with external beam radiotherapy to the whole pelvis (45 Gy in 2...

We present a formalism for using functional imaging both to derive patient-specific radiobiological properties and consequently to prescribe optimal non-uniform radiotherapy dose distributions. The ability to quantitatively assess the response to an initial course of radiotherapy would allow the derivation of radiobiological parameters for individual patients. Both an iterative optimization and...

— For given positive integers a, b, q we investigate the density of solutions (x, y) ∈ Z to congruences ax+ by ≡ 0 mod q.