نتایج جستجو برای: quantitative traits loci salinity

تعداد نتایج: 470036  

Journal: :Journal of immunology 2003
Jenny Karlsson Xiangshan Zhao Irina Lonskaya Malin Neptin Rikard Holmdahl Asa Andersson

The B10.RIII mouse strain (H-2(r)) develops chronic experimental autoimmune encephalomyelitis (EAE) upon immunization with the myelin basic protein 89-101 peptide. EAE was induced and studied in a backcross between B10.RIII and the EAE-resistant RIIIS/J strain (H-2(r)), and a complete genome scan with microsatellite markers was performed. Five loci were significantly linked to different traits ...

Journal: :Current Biology 2013
John F.Y. Brookfield

Quantitative trait loci (QTLs) underlying multifactorial disorders explain little of the heritability - most is 'missing'. A new yeast study has identified QTLs which explain most heritability in traits. Why is heritability missing in human diseases but not here?

Journal: :BMC Proceedings 2007
Aurelie Labbe Marie-Paule Roth Pierre-Hugues Carmichael Maria Martinez

We evaluate the impact of three pre-processing methods for Affymetrix microarray data on expression quantitative trait locus (eQTL) mapping, using 14 CEPH Utah families (GAW Problem 1 data). Different sets of expression traits were chosen according to different selection criteria: expression level, variance, and heritability. For each gene, three expression phenotypes were obtained by different...

2012
Samir N. P. Kelada David L. Aylor Bailey C. E. Peck Joseph F. Ryan Urraca Tavarez Ryan J. Buus Darla R. Miller Elissa J. Chesler David W. Threadgill Gary A. Churchill Fernando Pardo-Manuel de Villena Francis S. Collins

Hematological parameters, including red and white blood cell counts and hemoglobin concentration, are widely used clinical indicators of health and disease. These traits are tightly regulated in healthy individuals and are under genetic control. Mutations in key genes that affect hematological parameters have important phenotypic consequences, including multiple variants that affect susceptibil...

Journal: :Journal of dairy science 1999
R J Spelman A E Huisman S R Singireddy W Coppieters J Arranz M Georges D J Garrick

Seven New Zealand Holstein-Friesian families and two Jersey families, a total of 274 sires, were analyzed in a granddaughter design for marker-quantitative trait loci associations. For 17 nonproduction traits (management, size, and conformation traits), an across-family analysis was undertaken using multimarker regression procedures. Threshold levels were set empirically by permuting the data. ...

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