The Medical Journal of Australia ISSN: 0025729X 7 March 2005 182 5 235-236 ©The Medical Journal of Australia 2005 www.mja.com.au Lessons from practice nephritis induced by esomeprazole, along with six renal failure and two of renal impairment. In October 2004, the manufacturer of esomep Zeneca, reported being aware of at least 15 cases acute interstitial nephritis possibly induced by esom at le...

Article history: Received on: 17/06/2016 Revised on: 24/07/2016 Accepted on: 04/08/2016 Available online: 26/09/2016 Proton pump inhibitors (PPIs) are the most widely prescribed class of gastrointestinal drugs as they have minimal side effects and few significant drug interactions, and are generally considered safe for long-term treatment. The proton pump inhibitors such as omeprazole, esomepra...

Epidemiological, endoscopic and pathophysiological studies confirm the relationship between obesity gastroesophageal reflux disease (GERD) is characterized by a more severe course, has clinical features. In treatment of GERD, it necessary to use an individualized integrated approach, which consists in combined diet therapy, lifestyle changes drug therapy. The basis pharmacotherapy for GERD are ...

BACKGROUND AND PURPOSE There is controversy and little information about whether individual proton pump inhibitors (PPIs) differentially alter the effectiveness of clopidogrel in reducing ischemic stroke risk. We, therefore, aimed to elucidate the risk of ischemic stroke among concomitant users of clopidogrel and individual PPIs. METHODS We conducted a propensity score-adjusted cohort study o...

Controlled and sustained drug delivery has become the standard in modern pharmaceutical design and an intensive research work is going on in obtaining better drug product effectiveness, reliability and safety. In this regard, many polymers are very useful with majority of hydrogels, which undergo reversible volume and/or sol-gel phase transitions in response to physiological or other external s...

The mol-ecule of the title compound, C(31)H(29)N(3), contains a hexyl chain, a coordination unit (benzimidazole) and a functional group (carbazole). The benzimidazole ring is not coplanar with either the phenyl ring or the carbazole system, making dihedral angles of 43.26 (3) and 39.03 (2)°, respectively. The dihedral angle between the phenyl ring and the carbazole system is 24.42 (3)°. The hex...