The Abbott TDx therapeutic drug-monitoring system is based on fluorescence polarization. Polarization fluoroimmunoassay makes use of competitive binding, measuring the tracer binding directly, without the need for separation procedures. The attraction of non-radioactive polarization fluoroimmunoassay for the determination of T-uptake is that there is no radiation hazard and that the homogeneous...

Different types of telecommunication antennas, especially BTS antennas established in residential areas, emit radio frequency (RF) electromagnetic energy. So, community concerns over the health effects from their exposure are growing. To perform hazard assessment related to radio frequency radiation both at telecommunications sites and residential areas, and also to ensure compliance with natio...

Naturally occurring radioactive materials (NORMS) and fallout 137Cs were estimated in surface soils from the highly mineralized Singhbhum region of Eastern India. The activity concentrations varied from 50.67-109.14 Bq/kg (238U), 48.12142.55 Bq/kg (226Ra), 28.73-89.78 Bq/kg (232Th), 494.84-1121.36 Bq/kg (40K) and 1.8-7.48 Bq/kg (137Cs). Correlation between radionuclides was studied. 232Th/238U ...

Soil samples from three major towns and a holiday settlement in uranium-rich western Namibia have been analysed using a HPGe detector for radioactivity due to 238U, 232Th and 40K. The average activity concentrations of the radionuclides in the towns and settlement vary from a low of 18.6 ± 4.6 to a high of 69.6 ± 26.3 Bq kg−1 for 238U, 23.8 ± 8.4 to 91.1 ± 41.0 Bq kg−1 for 232Th and 460.3 ± 76....

PURPOSE To evaluate the influence of timing of salvage and adjuvant radiation therapy on outcomes after prostatectomy for prostate cancer. METHODS Using the Surveillance, Epidemiology, and End Results-Medicare linked database, we identified prostate cancer patients diagnosed during 1995-2007 who had one or more adverse pathological features after prostatectomy. The final cohort of 6,137 eligi...

Laser sources are nowadays largely adopted in medicine and hence they are widespread in medical environment, where patients are present and the users are not always highly specialized in managing laser sources. This has greatly boosted the attention towards safety issues related to exposure to laser beams and to strictly assess the values of well defined laser radiation standard parameters char...

PURPOSE Both humans and software are notoriously challenging to account for in traditional hazard analysis models. The purpose of this work is to investigate and demonstrate the application of a new, extended accident causality model, called systems theoretic accident model and processes (STAMP), to radiation oncology. Specifically, a hazard analysis technique based on STAMP, system-theoretic p...

BACKGROUND This study examined the association between functional single-nucleotide polymorphisms in candidate genes from oxidative stress pathways and risk of radiation pneumonitis (RP) in patients treated with thoracic radiation therapy for locally advanced lung cancer. METHODS A review was conducted of 136 patients treated with radiation therapy for lung cancer between 2001 and 2007, and w...

BACKGROUND Low-flow, low-gradient aortic stenosis (AS), associated with a poor prognosis, can be caused by a reduced stroke volume despite a preserved ejection fraction (left ventricular ejection fraction). We hypothesized that impaired ventricular diastolic filling secondary to constrictive pericarditis (CP) could contribute to reduced transaortic gradients in patients with AS+CP. We sought to...