A striking characteristic of endemic Antarctic brown algae is their broad vertical distribution. This feature is largely determined by the shade adaptation in order to cope with the seasonal variation in light availability. However, during spring-summer months, when light penetrates deep in the water column these organisms have to withstand high levels of solar radiation, including UV. In the p...

The primary intention of NASA’s Remote Exploration and Exploration (REE) project is to use commercial off-the-shelf, scalable, low-power, fault-tolerant, high-performance computation in space. Most of the faults caused by the radiation environments in regions of space of interest to REE (Deep Space, Low Earth Orbit) are transient, single event effects. Some of these faults can cause errors at d...

The immunosuppressant cyclophosphamide easily induces specific immunological tolerance in CBA mice, but is unable to produce an immunological defect in adult thymectomized animals. In contrast, lethal (and sublethal) irradiation does not induce tolerance but readily brings out the deficit of thymectomy. Furthermore, bone marrow cells which protect lethally irradiated animals do not prevent drug...

We aimed to investigate the relationship between the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and the radiation tolerance of patients with head and neck squamous cell carcinoma (HNSCC). From January 2015 to January 2016, 117 patients with HNSCC were enrolled in our study and assigned into the sensitive and tolerance groups based on curative effect. Immunohistochemist...

The radiation treatment of intra-oral cancer involves technics combining intra-oral radium applications directly to the primary seat of the disease and external radiation to the glandular regions of the neck. The problem of the primary lesion has been successfully met by electrosurgical methods, radium seed implantations directly into and about the site of the disease, and by heavily filtered r...

Background: In conventional radiation therapy, regarding normal tissue tolerance, the treatment of bulk tumors is one of the remaining challenges. Grid Radiation Therapy (GRT) is a technique to deliver high doses, approximately 15 – 20 Gy per fraction, to several small volumes located in a large radiation field. This can be performed using a grid block. The current work has concentrate...

AIM The present phase II study aimed to evaluate the tolerance and safety of Dixentil, a nutritional supplement based on zinc with the addition of prebiotics (galacto-oligosaccharides), tyndalized probiotics (Lactobacillus acidophilus and L. casei) and vitamins B1, B2 and B6, and nicotinamide), given as prophylaxis to patients undergoing pelvic radiotherapy and its efficacy in the prevention an...

................................................................................................................... 1 SAMMANFATTNING ................................................................................................... 3 LIST OF PAPERS ........................................................................................................... 5 ABBREVIATIONS ..........................

PURPOSE To study Heat Shock Proteins (HSP) expression in patients subjected to radiotherapy and their potential use as biomarkers for radiation tolerance. An evaluation is also made of whether irradiated volume is critical to the outcome of normal tissue injury using polymorphonuclear neutrophils as biosensors, and whether HSP antibodies (Ab) may be involved in post-radiotherapy disease. MATE...

Radiation nephropathy was first recognized in 1906. The kidney is a radiosensitive organ with a tolerance dose (5% complications in 5 years) of 20 Gray. The imaging findings of acute and chronic radiation induced renal injury are previously described. Radiation-induced adrenal injury, to our knowledge, has not been described in the literature. Unlike the kidneys and other upper abdominal organs...