نتایج جستجو برای: rag2
تعداد نتایج: 856 فیلتر نتایج به سال:
The majority of Atm-deficient mice die of malignant thymic lymphoma by 4-5 mo of age. Cytogenetic abnormalities in these tumors are consistently identified within the Tcr alpha/delta locus, suggesting that tumorigenesis is secondary to aberrant responses to double-stranded DNA breaks that occur during V(D)J recombination. Since V(D)J recombination is a recombinase-activating gene (RAG)-dependen...
Mycobacterium abscessus is an emerging rapidly growing mycobacterium that causes tuberculous-like lesions in humans. We studied the immune control of this organism in C57BL/6 mice challenged intravenously with 10(7) CFU. Bacteria were eliminated from both the spleen and the liver within 90 days, and liver histology showed organized granulomatous lesions. A T- and B-cell requirement was investig...
the tropical asian cyprinid genus puntius is a major part of the ichthyofauna in southeast asia. systematic status of the genus puntius among cyprinidae, the most prominent freshwater fish all over the world, remain to be substantiated. the molecular phylogenetic analyses derived from recombination activating genesequences (rag2) for 35 representative samples of malaysian puntius and their alli...
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