Adoptive immunotherapy with donor lymphocyte infusions (DLI) is an effective treatment for relapsed chronic myeloid leukemia (CML) after allogeneic stem cell transplantation. To identify the effector and target cell populations responsible for the elimination of the leukemic cells in vivo we developed an assay to measure the frequency of T lymphocyte precursor cells capable of suppressing leuke...

The in vitro production of interleukin-1 in 15 children with acute hepatitis A and five children with acute hepatitis B was determined by measuring lymphocyte activating factor secreted by peripheral blood monocytes in a thymocyte proliferation assay. Aluminium hydroxide induced production of lymphocyte activating factor was significantly lower in patients with acute hepatitis A as well as pati...

Background: The struggle of humanity with Coronavirus disease 2019 (COVID-19) infection, which affected the whole world and caused severe social health crises, continues without deceleration. Objectives: This study aimed to determine relationship between abnormal laboratory parameters upon admission intensity lung involvement using chest computerized tomography severity score (CT-SS). Methods: ...

Background/Aim: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a pandemic. Early diagnosis of complications and mortality this will guide the treatment process patients with COVID-19. We aimed to investigate whether neutrophil/lymphocyte fibrinogen/albumin ratios can predict COVID-19 patients. Methods: A total 102 adult...

Background: Hepsin is known as a cell-surface serine protease expressed predominantly in the liver. Hepsin-deficient mice show resistance to high-fat diet-induced obesity, hyperlipidemia, and hyperglycemia. Up present, physiological function of hepsin has not been fully determined. may play significant specific roles diabetes. Objectives: This study aimed evaluate relationship between protein c...

The neutrophil/lymphocyte ratio (NLR) and the lymphocyte/C-reactive protein (LCR) are prognostic factors in inflammatory, cardiovascular, oncological diseases. With emergence of COVID-19 pandemic, it has been recently shown that NLR LCR also useful for prognosis disease severity patients infected with SARS-CoV-2 virus at sea level. However, there no studies demonstrating reliability high-altitu...

With limited sample sizes and varying study outcomes regarding complete blood count (CBC)-associated biomarkers their febrile seizure (FS) classification, along with research on osmolarity, this aims to evaluate CBC-associated biomarkers, including for a comprehensive view of diagnostic value. This single-center retrospective used data from 364 children (aged 5–60 months) diagnosed FS. The pati...

Background/Aim. Measles is a contagious disease with good prognosis; however, severe complications may sometimes develop. C-reactive protein (CRP) and blood cells count-derived inflammatory indices ? granulocyte-lymphocyte ratio (GLR), platelet to lymphocyte (PLR), monocyte (MLR), mean plate-let volume (MPV)/platelet count (MPR), red cell distribution width (RDW), MPV are the indicators related...

Introduction: The complete blood picture of patients with COVID-19 showed lymphocytopenia and neutrophilia. Changes in the circulating cells are served as prognostic factors COVID-19. This study aimed to investigate clinical importance determining hematological indices ratios diagnostic and/or markers Methods: cross-sectional observational was performed West Erbil Emergency Hospital, Kurdistan ...