background: gastric cancer (gc) is one of the most commonly diagnosed malignancies. genetic variation in genes encoding cytokines and their receptors, determine the intensity of the inflammatory response, which may contribute to individual differences in the outcome and severity of the disease. interleukin-10 (il-10) is a multifunctional cytokine with both immunosuppressive and antiangiogenic f...

BACKGROUND/AIMS Relapses of Crohn's disease are difficult to predict. We assessed the value of serum level of interleukin-6, tumour necrosis factor alpha (TNF-alpha) and soluble TNF receptors as predictors of relapse in quiescent Crohn's disease. PATIENTS/METHODS Thirty-six patients with inactive Crohn's disease, treated or not, were included. Various clinical and biological parameters, inclu...

background: interleukin-19, a member of the interleukin-10 family of cytokines, contributes to breast cancer pathogenesis. high interleukin-19 expression in breast tumor tissues is associated with poor clinical outcome. this study aimed to assess the changes in serum level of interleukin-19 in breast cancer patients in comparison with normal women and its association with the clinicopathologica...

Innate immunity is the organism’s first line of defence, and receptors immune cells play a key role. Interleukin 1 receptor-associated kinase 4 (IRAK1 IRAK4) are necessary for signal transmission from Toll-like receptors, which most important cells. The main objective this study was to investigate gene polymorphisms IRAK1 IRAK4 in Czech Fleckvieh cattle (CF) to compare their diversity with...