نتایج جستجو برای: recombinant protein stability

تعداد نتایج: 1565311  

Journal: :Journal of molecular biology 1999
T K Chaudhuri K Horii T Yoda M Arai S Nagata T P Terada H Uchiyama T Ikura K Tsumoto H Kataoka M Matsushima K Kuwajima I Kumagai

The structure, stability, and unfolding-refolding kinetics of Escherichia coli-expressed recombinant goat alpha-lactalbumin were studied by circular dichroism spectroscopy, X-ray crystallography, and stopped-flow measurements, and the results were compared with those of the authentic protein prepared from goat milk. The electric properties of the two proteins were also studied by gel electropho...

Farzaneh Rabiee Hossein Baharvand Kamran Ghaedi Khadijeh Karbalaei Malihe Nazari Jahantigh Maryam Ostad Sharif Marzieh Nematollahi Mehran Miroliaei Mohamad Hossein Nasr Isfahani Shahnaz Razavi Somayeh Tanhaei

Epitope tagging is a method of expressing proteins whereby an epitope for a specific monoclonal antibody is fused to a target protein using recombinant DNA techniques. The aim of this study was to sub-clone the peroxisomal protein (PEP) cDNA into a mammalian expression vector leading to the formation of a  chimeric PEP-cDNA containing the FLAG epitope. The FLAG-PEP recombinant cDNA was construc...

Journal: : 2022

Induction of DrsB1-CBDAvr4 Recombinant Protein in Hairy and Adventitious Roots T1 Transgenic Plants

Journal: :iranian journal of microbiology 0
somayeh kiaie department of microbiology and immunology, school of medicine, arak university of medical sciences, arak, iran. hamid abtahi department of microbiology and immunology, school of medicine, arak university of medical sciences, arak, iran and molecular and medicine research center, arak university of medical sciences, arak, iran. ghasem mosayebi molecular and medicine research center, arak university of medical sciences, arak, iran. mohammadyosef alikhani department of microbiology, school of medicine, hamedan university of medical sciences, hamedan, iran. iraj pakzad clinical microbiology research center, ilam university of medical sciences, ilam, iran and department of microbiology, school of medicine, ilam university of medical sciences, ilam, iran.

background   and   objectives:    the   toxin   co-regulated   pilus   a   (tcpa)   has   been   described   as   a   criti- cal  pathogenicity  factor  of   vibrio  cholerae .  tcpa  is  a  candidate  for  making  subunit  vaccine  against  chol- era.  the  aim  of  this  study  was  to  produce  a  candidate  vaccine  by  expressing  recombinant  tcpa  in   e.  coli . materials and methods: i...

Journal: :avicenna journal of medical biotechnology 0

background: various prokaryotic and eukaryotic expression systems have been developed for the production of recombinant proteins. in the present study, we used a new protein expression system based on the iranian lizard leishmania, a trypanosomatid protozoan as a host, for the expression of lpg3 gene from leishmania infantum (l.infantum). methods: the lpg3 gene was cloned in the expression cass...

Journal: :journal of cell and molecular research 0
zahra roudbari mohammadreza nassiri mojtaba tahmoorespur aliakbar haddad-mashadrizeh ali javadmanesh

human growth hormone (hgh) is a protein with multiple roles in a range of biological functions such as protein, carbohydrates and lipid metabolisms as well as immunity, tissue development and overall growth. one of the major class of biopharmaceuticals in mammalian cells is the production of recombinant pharmaceutical proteins. in this study, we constructed a lentiviral vector carrying coding r...

Journal: :نشریه آزمایشگاه پزشکی 0
nogol omoumi department of biology, science and research branch, islamic azad university, tehran, iran mohammad-ali shokrgozar national cell bank, pasteur institute of iran, tehran, iran zahra noormohammadi department of biology, science and research branch, islamic azad university, tehran, iran

background and objective: use of elastin-like proteins (elps) provides high-performance protein purification without need for chromatography. in line with cost reduction and facilitation of recombinant proteins purification, which represent a high percentage of production costs, in this project, we eliminated the need for proteases in the process of separation of recombinant proteins from elp b...

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