The time evolution of a Munch pressure-flow translocation system is calculated using a numerical computer method. Results are obtained for the time course of the system variables following application of a large resistance in the translocation path, intended to simulate a cold block. The resistance factor required to produce translocation inhibition indicates that even moderate inhibition is pr...

BACKGROUND Acute insulin-like growth factor-1 administration has been shown to have beneficial effects in cardiac pathological conditions. The aim of the present study was to assess the structural and ex vivo functional impacts of long-term cardiomyocyte-specific insulin-like growth factor-1 overexpression in hearts of transgenic αMHC-IGF-1 Ea mice. METHODS Performance of isolated transgenic ...

ventilation tube (vt) insertion is the most common otologic operations performed in children, which has great importance in recovery and prevention of hearing loss in children with eustachian tube dysfunction in critical ages of growth development. the location of the vt insertion varies in different studies; the differences are in recovery rates and sequelae of vt insertion. this study is perf...

As the cloud era begins and failures become commonplace, failure recovery becomes a critical factor in the availability, reliability and performance of cloud services. Unfortunately, recovery problems still take place, causing downtimes, data loss, and many other problems. We propose a new testing framework for cloud recovery: FATE (Failure Testing Service) and DESTINI (Declarative Testing Spec...

Background The Recovery Knowledge Inventory (RKI) is one of the influential scales to assess knowledge and attitude toward recovery-oriented practices among mental health service providers. In the present study, we aimed to develop a Japanese version of RKI and examine the validity and reliability. Methods We translated RKI into Japanese by reference to the guidelines for translating and adap...

BACKGROUND Interleukin-6 (IL-6) and macrophage colony stimulating factor plasma levels are elevated in acute coronary syndromes. IL-6 has an inherent negative inotropic action and, with tissue factor (TF), mediates the ischemia-reperfusion myocardial injury. We hypothesized that inducible ischemia leads to cytokine production, TF expression, and consequently persistent left ventricular dysfunct...

This paper introduces an effective production optimization and a water injection allocation method for oil reservoirs with water injection. In this method, a two-stage adaptive simulated annealing (ASA) is used. A coarse-grid model is made based on average horizon permeability at the beginning iterations of the optimization to search quickly. In the second stage, the fine-grid model is used to ...

In ASP (Alkali-Surfactant-Polymer) flooding processes, surfactants help to enhance oil recovery by lowering the interfacial tension between the oil and water. However, due to the high cost of surfactants and the stability of the emulsion that varies with surfactant concentration, it is necessary to optimize the surfactant concentration in ASP flooding. In this study, we combined numerical simul...

In the absence of a successful mating, pheromone-arrested Saccharomyces cerevisiae cells reenter the mitotic cycle through a recovery process that involves downregulation of the mating mitogen-activated protein kinase (MAPK) cascade. We have isolated a novel gene, POG1, whose promotion of recovery parallels that of the MAPK phosphatase Msg5. POG1 confers alpha-factor resistance when overexpress...

BACKGROUND Patients who undergo mechanical support with a left ventricular assist device (LVAD) exhibit reverse remodeling and in some cases recover from heart failure. We have developed a combination therapy using LVAD support combined with pharmacological therapy to maximize reverse remodeling, followed by the beta2 adrenergic agonist clenbuterol. We recently found that clenbuterol induces in...