BACKGROUND AND PURPOSE The aim was to evaluate the spacer dimensions and prostate position variability during the course of radiotherapy for prostate cancer. MATERIALS AND METHODS CT scans were performed in a group of 15 patients (G1) after the 10 ml injection of a hydrogel spacer (SpaceOAR™) and 30 patients without a spacer (G2) before the beginning of treatment (CT1) and in the last treatme...

The purpose of this study is to compare three-dimensional conformal radiotherapy (3D-CRT) plans in a setting of salvage radiotherapy after radical prostatectomy (RP) and to simulate whether dose escalation is possible with the most adequate 3D-CRT technique. This study included consecutive 10 patients underwent salvage radiotherapy (RT) for biochemical relapse of prostate cancer after RP. Norma...

PURPOSE We aimed to analyze the treatment outcome and long-term toxicity of 70 Gy hypofractionated intensity-modulated radiotherapy (IMRT) for localized prostate cancer using a customized rectal balloon. MATERIALS AND METHODS We reviewed medical records of 86 prostate cancer patients who received curative radiotherapy between January 2004 and December 2011 at our institution. Patients were de...

The aims of this study were twofold: first, to determine the impact of variance in dose-volume histograms (DVH) on patient-specific toxicity after 2 high-dose fractions in a sample of 22 men with prostate cancer; and second, to compare the effectiveness of traditional DVH analysis and principal component analysis (PCA) in predicting rectum and urethra toxicity. A series of 22 patients diagnosed...

background: to evaluate the dosimetric difference between conventional and three-dimensional conformal radiotherapy (3d-crt) using 6 and 18 mv x-ray photons. materials and methods: computed tomography scans of 26 pelvic patients were acquired and transferred to the 3d treatment planning system. for each patient, 8 conventional plans (3, 4, 5 and 6 fields) and one 3d-crt plan were prepared using...

AIM To assess target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment and to assess possibility of safety margin reduction. BACKGROUND Implementation of IGRT should influence safety margins. Utilization of cone-beam CT provides current 3D anatomic information directly in irradiation position. Such information enables reconstruction of the actual dose d...

AIMS Intraoperative radiotherapy (IORT) for locally advanced rectal cancer as an integral part of multimodal treatment, may lead to reduced local recurrence but it is not routinely used. The aim of this paper is to describe our experience with IORT in the treatment of patients with locally advanced adenocarcinoma of the lower third of the rectum. MATERIAL AND METHODS Laparoscopic abdominoperi...

RODRIGUES G. Is intensity-modulated radiotherapy for prostate cancer ready for prime-time? Can J Urol 2012;19(4):6381-6382. the therapeutic ratio between the positive anticancer effect of radiotherapy on macroscopic and microscopic disease and the negative normal tissue effects leading to both acute and late radiotherapy toxicities. In the context of prostate cancer radiotherapy, these technolo...

Cases of synchronous prostate and colorectal adenocarcinomas have been sporadically reported. There are case reports on patients with synchronous prostate and rectal cancers treated with external beam radiotherapy alone or combined with high-dose rate brachytherapy boost to the prostate. Here, we illustrate a patient with synchronous prostate and rectal cancers treated using the volumetric arc ...

Indium-111 radioimmunoscintigraphy (RIS) has an increasing role in the treatment of prostate cancer and is most commonly performed at this disease site using labeled monoclonal antibody against prostate-specific membrane antigen. There are many limitations of RIS, including low spatial resolution, low diagnostic yield and limited availability. Despite these limitations, the efficacy of RIS has ...