background the incidence and mortality rates of breast cancer are high among filipino women. the lack of knowledge on preventive behavior and early detection related to breast cancer is considered a reason. conclusions women who were aware of risk factors for breast cancer possessed a higher education level and had knowledge of the association of risk factors with preventive behaviors and early...

breast metastasis of ovarian carcinoma is rare. to date, only 39 cases have been reported in the english-language  literature  so  far.  we  are  herewith  reporting  a  primary  ovarian  papillary  serous  cyst adenocarcinoma metastasing to breast and epsilateral supraclavicular node in a 58 year old female asthe first case in our centre, located at north-east india.  the purpose of reporting ...

background breast cancer is the most common malignancy in women around the world so finding new biomarkers for early detection and also study on molecular aspects of breast cancer is valuable. cancer testis genes are a group of genes expressed solely in testis and in a range of human malignancies. objectives in this study we determined the expression of cancer testis genes tsga10, tex101 and od...

Developed two decades ago, oncogenetic medical practice mainly concern breast, ovarian and colorectal cancers, and is targeting the hereditary risk factor, the only one that shows positive predictive value justifying the molecular diagnosis. Screening for BRCA1 and BRCA2 gene mutations is standard practice today for hereditary breast and ovarian cancer (HBOC) families in developed countries, of...

The prognostic value of components of the urokinase-type plasminogen activator (uPA) system, its receptor uPAR (CD87), and plasminogen activator inhibitors PAI-1 and PAI-2 is well established. We studied the predictive value of these proteolytic factors by evaluating the association of their tumor expression level and the efficacy of tamoxifen therapy in patients with recurrent breast cancer. T...

background: breast cancer is the most common cancer and the leading cause of cancer death among the women worldwide. the risk of local and distant recurrence is the highest during the first two years following the initial treatment. very late relapse (after 12 years) is uncommon in breast cancer survivors. methods: herein, we report the characteristics and outcomes of 6 such cases of breast can...

objective: the objective of this study was to investigate inhibition and anti-cancer effects of linoleic acid on the mcf-7 and mda-mb-231 human breast cancer cells. materials and methods: cell lines human breast cancer mcf-7 (gdc055) and mda-mb-231 (htb-26) cell lines were obtained from atcc. mcf-7 estrogen receptor positive human breast cancer cell line and  the estrogen receptor negative huma...

background: th e second leading cause of cancer deaths in women is breast cancer. germline mutations in susceptibility breast cancer gene brca1 increase the lifetime risk of breast cancer. eighty-one large genomic rearrangements (lgrs) have been reported up to date in brca1 gene, and evaluation of these rearrangements helps with precise risk assessment in high-risk individuals. in this study, w...

B reast cancer is the third most common form of cancer worldwide, after lung and stomach cancer, and is the most common cause of cancer death in women. The age-adjusted incidence rates of breast cancer are 176% higher in developed than developing countries. In Singapore, breast cancer is the most common cancer in women and the incidence rate in 1993–1997 was 2.3 times higher than in 1968–1972, ...

background: the relationship between thyroid autoimmunity and breast cancer is a challenging subject. we aimed to investigate this association in women with breast cancer. methods: in this descriptive study, 41 women with newly diagnosed breast cancer before receiving any pharmacologic treatment and 38 healthy age-matched women were enrolled. anti tpo ab (anti-thyroid peroxidase antibodies), ft...