Abstract Background A rare cause of primary hyperparathyroidism (PHPT) is a parathyroid carcinoma. Hypercalcemia with an elevated hormone (PTH) level seen in recurrent and metastasis disease cases often refractory to medical therapy, thus surgical resection recommended when possible. We performed debulking surgery for pleural dissemination cancer improvement symptoms patient hypercalcemia. Case...

HYPOTHESIS Preoperative and intraoperative localizing techniques are more cost-effective than a nondirected bilateral neck exploration in the initial treatment of primary hyperparathyroidism (HPT). DESIGN A clinical outcome model was developed to simulate the surgical management of primary HPT. Clinical scenarios modeled included a nondirected bilateral neck exploration and surgery using the ...

Background Multiple endocrine neoplasia type 1 (MEN1) is an inherited syndrome caused by the mutation in tumor suppressor gene MEN1 . The recurrence rate of primary hyperparathyroidism (PHPT) patients with after parathyroidectomy remains high, and management recurrent still challenging. Case presentation We reported a 44-year-old woman combined PHPT who was diagnosed through genetic screening p...

Maternal primary hyperparathyroidism causing hypercalcemia during pregnancy can suppress fetal and neonatal parathyroid hormone secretion. We report a newborn with transient hypoparathyroidism presented by hypocalcemic seizure and tetany on the 21st postnatal day in whom the final diagnosis was asymptomatic maternal primary hyperparathyroidism. Neonatal hypocalcemia usually occurs early in life...

Maternal hypercalcemia suppresses parathyroid activity in the fetus resulting in impaired parathyroid responsiveness to hypocalcemia after birth. Resultant hypocalcemia may be severe and prolonged and rarely may lead to convulsions. Here, we present a newborn infant admitted to the pediatric emergency department at age two weeks with recurrent tonic convulsions due to asymptomatic maternal hype...

Fahrs syndrome is a rare anatomoclinical entity whose main etiology primary or postoperative hypoparathyroidism. It characterized by bilateral and symmetrical intracerebral calcifications, localized in the basal ganglia. Hypoparathyroidism, postoperative, most classic anomaly. Hyperparathyroidism exceptionally reported as cause of Fahr syndrome. We report case 30-year-old woman who presented wi...

To report a rare case of axis brown tumor and to review literature of cervical spine brown tumor. Brown tumor is a rare bone lesion, incidence less than 5% in primary hyperparathyroidism. It is more common in secondary hyperparathyroidism with up to 13% of cases. Brown tumor reactive lesion forms as a result of disturbed bone remodeling due to long standing increase in parathyroid hormones. Cer...

BACKGROUND Primary hyperparathyroidism is an endocrinopathic condition characterized by hypersecretion of parathyroid hormone. Excess parathyroid hormone results in an altered state of osseous metabolism involving bone resorption and tissue change known as osteitis fibrosa cystica, which is the end stage of primary hyperparathyroidism. Osteitis fibrosa cystica is associated with the development...