Thermal lesions were produced in 12 male Wistar rats, positioning a massive aluminum bar 10 mm in diameter (51 g), preheated to 99°C ± 2°C/10 min. on the back of each animal for 15 sec. After 7, 14, 21, and 28 days, animals were euthanized. The edema intensity was mild, with no bubble and formation of a thick and dry crust from the 3rd day. The percentage of tissue shrinkage at 28 days was 66.6...

This study aimed at evaluating the use of hydrogel isolectin in the treatment of second-degree burns. Twenty male rats were randomly divided into two groups (G1 = treatment with hydrogel containing 100 μg/mL Cramoll 1,4 and G2 = Control, hydrogel). After 7, 14, 21, 28, and 35 days, animals were euthanized. On the 7th day, G1 showed intense exudates, necrosis and edema. On the 14th day, G1 showe...

Fracture blisters are tense vesicles that arise on markedly swollen skin overlying traumatized soft tissue. While this relatively uncommon complication has been well described in the trauma literature, this article reports for the first time a case of fracture blisters after primary total knee arthroplasty. The fracture blisters developed within 36 hours of surgery and were associated with prof...

We have determined the complex sequence of events from the point of injury until reepithelialization in axolotl skin explant model and shown that cell layers move coherently driven by cell swelling after injury. We quantified three-dimensional cell migration using correlation spectroscopy and resolved complex dynamics such as the formation of dislocation points and concerted cell motion. We qua...

Diabetic ulcers (DU), common pathology for diabetic patients, is a chronic wound which struggle to heal and may require amputation of the lower legs. We propose replicate complete human skin an endothelialized dermal tissue in laboratory using cells extracted from patients treatment development. Populations fibroblasts keratinocytes were isolated patient harvested after foot amputation. The dWH...

Abstract The plant Stryphnodendron adstringens is a species of legume in the genus that found Brazil. It also known as “barbatimão-verdadeiro” and it popularly used folk medicine due to its healing properties. Purpose: aim this study was evaluate activity hydrogel, together with an S. hydroalcoholic extract, diabetic non-diabetic rats. Methods: phytochemical analysis extract evaluated through H...

IMPORTANCE Despite the advantages and reduced recovery time of ablative fractional photothermolysis, patients still seek adjuvant treatments to reduce healing time and facilitate their return to normal social and work activity. Platelet-rich plasma (PRP) has been used for many applications in various surgical fields for its ability to improve wound healing, hemostasis, and graft survival. OBJ...