نتایج جستجو برای: reeves fr

تعداد نتایج: 12731  

2005

Lloyd TC (1966b) Role of nerve pathways in the hypoxic vasoconstriction of lung. J Appl Physiol 21: 1351-1355 McMurtry IF, Davidson AB, Reeves JT, Grover RF (1976) Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs. Circ Res 38: 99-104 Mills E, Jobsis FF (1972) Mitochondrial respiratory chain of carotid body and chemoreceptor response to changes in oxy...

Journal: :Annals of neurology 2009
Jennifer A Ogren Charles L Wilson Anatol Bragin Jack J Lin Noriko Salamon Rebecca A Dutton Eileen Luders Tony A Fields Itzhak Fried Arthur W Toga Paul M Thompson Jerome Engel Richard J Staba

OBJECTIVES There is compelling evidence that pathological high-frequency oscillations (HFOs), called fast ripples (FR, 150-500Hz), reflect abnormal synchronous neuronal discharges in areas responsible for seizure genesis in patients with mesial temporal lobe epilepsy (MTLE). It is hypothesized that morphological changes associated with hippocampal atrophy (HA) contribute to the generation of FR...

Journal: :Genetics 1995
S He A Lyznik S Mackenzie

Two nuclear genes, Fr and Fr2, have been identified that restore pollen fertility to cytoplasmic male sterile (CMS) common bean (Phaseolus vulgaris L.) by apparently distinct mechanisms. Whereas Fr2 appears to suppress the expression of a male sterility associated mitochondrial sequence (designated pvs), Fr restores pollen fertility by causing the elimination of this unusual mitochondrial DNA-s...

Journal: :Applied and environmental microbiology 2009
Shi Chen Xiangzhao Mao Yaling Shen Yongjun Zhou Jialiang Li Lianrong Wang Xinyi Tao Liang Yang Yuxiao Wang Xiufen Zhou Zixin Deng Dongzhi Wei

Tailoring steps are often important for the activity of mature antibiotics. Here, we report that novel decarboxylated FR-008/candicidin derivatives were obtained from the P450 monooxygenase gene fscP mutant of Streptomyces sp. strain FR-008. The toxicity of decarboxylated FR-008/candicidin derivatives has been shown to be greatly reduced compared to that of wild-type FR-008/candicidin.

2007
Luc Hogie

Alain Cardon President of the jury University of Paris VI (FR) Pascal Bouvry Supervisor University of Luxembourg (LU) Frédéric Guinand Supervisor University of Le Havre (FR) Serge Chaumette Reviewer University of Bordeaux (FR) Marco conti Reviewer CNR, Pisa (IT) Steffen Rothkugel Member University of Luxembourg (LU) Enrique Alba Member University of Málaga (ES) Michel Syska Member INRIA/Univers...

Journal: :Blood 2009
Wei Xia Andrew R Hilgenbrink Eric L Matteson Michael B Lockwood Ji-Xin Cheng Philip S Low

Previous work has demonstrated that a subset of macrophages expresses a folate receptor (FR) that can mediate internalization of folate-linked molecules, including imaging and therapeutic agents. To characterize this subset, macrophages were collected from peritoneal cavities of mice injected with saline, thioglycolate, zymosan, heat-killed or live bacteria, and cell-surface markers that coexpr...

2004
Alexander Poltorak

The spacetime ontology is considered in General Relativity (GR) in view of the choice of a frame of reference (FR). Various approaches to a description of the FR, such as coordinate systems, monads and tetrads are reviewed. It is shown that any of the existing FR definitions require a preexisting background spacetime, which, if defined independently of the FR, renders the spacetime absolute in ...

Journal: :Blood 2014
Monica Messina Ilaria Del Giudice Hossein Khiabanian Davide Rossi Sabina Chiaretti Silvia Rasi Valeria Spina Antony B Holmes Marilisa Marinelli Giulia Fabbri Alfonso Piciocchi Francesca R Mauro Anna Guarini Gianluca Gaidano Riccardo Dalla-Favera Laura Pasqualucci Raul Rabadan Robin Foà

Fludarabine refractoriness (FR) represents an unsolved clinical problem of chronic lymphocytic leukemia (CLL) management. Although next-generation sequencing studies have led to the identification of a number of genes frequently mutated in FR-CLL, a comprehensive evaluation of the FR-CLL genome has not been reported. Toward this end, we studied 10 FR-CLLs by combining whole-exome sequencing and...

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