The use of nanomaterials for improving drug delivery methods has been shown to be advantageous technically and viable economically. This study employed the use of halloysite nanotubes (HNTs) as nanocontainers, as well as enhancers of structural integrity in electrospun poly-e-caprolactone (PCL) scaffolds. HNTs were loaded with amoxicillin, Brilliant Green, chlorhexidine, doxycycline, gentamicin...

Streptolysins S and 0 from hemolytic streptococci were found to induce mitochondrial swelling and the release of malic dehydrogenase from mitochondria; no other streptococcal products were as active. Mg ++, cyanide, dinitrophenol, bovine serum albumin, and antimycin all inhibited streptolysin-induced mitochondrial swelling; only the latter two agents prevented release of malic dehydrogenase fro...

In the present paper, and agent based model is developed to balance the electric storage in a Hybrid Power Grid, where each house (end user) is modeled as an agent that can choose to store/release electricity at given times in order to tail the demand minimizing its own cost. The overall interaction of the agents causes the demand curve to change according to the decisions taken by the agents i...

Increasing concentrations of ethidium bromide cause progressive inactivation of ribosomes, apparently by binding to double-stranded regions of the rRNA. At low drug concentrations (10(-4)M) the partial inhibition detected is due to specific release of proteins L7 and L12; activity can be restored by addition of an excess of these two proteins. At higher concentrations the inactivation is not re...

1,3-Butylene glycol (1,3-butanediol) may be safely used in food in accordance with the following prescribed conditions: (a) The substance meets the following specifications: (1) 1,3-Butylene glycol content: Not less than 99 percent. (2) Specific gravity at 20/20 °C: 1.004 to 1.006. (3) Distillation range: 200°–215 °C. (b) It is used in the minimum amount required to perform its intended effect....

Abstract Invasive alien plants (IAPs) are a significant threat to the biodiversity and ecological functioning of sub-Antarctic Prince Edward Islands (PEIs); however, weed biological control has not yet been implemented as management tool. The PEIs have had 23 recorded, which several considered beyond eradication therefore could benefit from release safe effective biocontrol agents. We used Sout...

von Willebrand factor (vWF), an adhesive glycoprotein involved in primary hemostasis, is stored and released from endothelial secretory granules called Weibel-Palade bodies. Regulated secretion occurs in reaction either to [Ca(2+)](i)-raising agents (histamine or thrombin) or to cAMP-raising agents (epinephrine, adenosine, or forskolin). We investigated the pattern of release and the cytoskelet...