A method is described for detecting metastable transitions which take place with the release of kinetic energy in the field-free region between the source and electrostatic analyser of a doublefocusing mass spectrometer, and a procedure is given for evaluating the kinetic energy release. Values are given for a number of transitions and are in agreement with those obtained by other methods where...

Synthesis of mRNA in eukaryotes involves the coordinated action of many enzymatic processes, including initiation, elongation, splicing, and cleavage. Kinetic competition between these processes has been proposed to determine RNA fate, yet such coupling has never been observed in vivo on single transcripts. In this study, we use dual-color single-molecule RNA imaging in living human cells to co...

The kinetic of photo oxidative decolorization of C.I. Acid yellow 23 (AY23) was investigated in UV/ process. The semi-logarithmic of the concentrations of AY23 versus irradiation time were linear, suggesting pseudo-first order reaction. A simple kinetic model is proposed which confirms pseudo- first order reaction. The results indicate that the apparent reaction rate constant is a function of l...

objective(s): researchers have intended to reformulate drugs so that they may be more safely used in human body. polymer science and nanotechnology have great roles in this field. the aim of this paper is to introduce an efficient drug delivery vehicle which can perform both targeted and controlled antibiotic release using magnetic nanoparticles grafted ph-responsive polymer.  methods: fe3o4 na...

A Box-Behnken design with three replicates was used for preparation and evaluation of Eudragit vancomycin (VCM) nanoparticles prepared by double emulsion. The purpose of this work was to optimize VCM nanoparticles to improve the physicochemical properties. Nanoparticles were formed by using W1/O/W2 double-emulsion solvent evaporation method using Eudragit RS as a retardant material. Full factor...

To answer challenge of targeted and controlled drug release in oral delivery various materials were studied by different methods. In the present paper, controlled metal based drug (Pd(II) complex) release manner of β‑Lactoglobulin (β-LG) nanoparticles was investigated using mathematical drug release model in order to design and production of a new oral drug delivery system for gastrointestinal ...

Development of a novel delivery system has been attempted to deliver viable probiotic cells into the gut for a prolonged period of time while maintaining high numbers of viable cells within the formulation throughout the shelf-life of the product and during the gastrointestinal transit. Core mucoadhesive microspheres of Bacillus coagulans were developed employing several grades of hypromellose,...

The electron-nuclear dynamics of the Coulomb explosion of a large polyatomic molecule, anthracene, is probed using kinetic energy distributions of produced H+ ions. The kinetic energy release of ejected protons exceeds 30 eV for anthracene exposed to 10(14) W cm(-2), 800 nm pulses of 60 fs duration. We propose a strong-field charge localization model, based on nonadiabatic dynamics of charge di...

Six soil amendments including municipal solid waste compost (MSWC), coal fly ash (CFA), rice husk biochar prepared at 300°C (B300) and 600°C (B600), zerovalent iron (Fe0), and zerovalent manganese (Mn0) were evaluated to determine their ability to reduce mobility of chromium (Cr) in a Cr-spiked soil. The Cr-spiked soil samples were separately incubated with selected amendments at 2 and 5% [weig...