Abstract Background: Screening for patients at risk of renal scarring is a challenge in children with acute pyelonephritis (APN). Diuretic Tc-99m mercaptoacetyltriglycine (MAG3) scintigraphy with zero time injection of furosemide (MAG3-F0) was observed to display focal parenchymal disorders. The advantages of MAG3 include: lower radiation dose and short duration of the test. The aim of this st...

The kidneys regulate the body’s fluid, electrolyte, and acid-base balances while removing toxic substances from the blood and excreting them in urine. The kidneys also play a significant role in erythropoietin and prostaglandin synthesis, in insulin degradation, and in the renin-angiotensin-aldosterone system. Many common disease processes and injuries can interfere with normal renal function. ...

BACKGROUND HIV infection affects all body organs including kidney. Since the frequency of HIV-related renal disorders is unknown in Iran and the number of HIV-infected patients is increasing, this study was conducted for the first time in Iran to assess the frequency of electrolyte imbalance, renal failure, and proteinuria among HIV-infected patients. METHODS Between April and December 2005, ...

On the assumption that increased urinary lysozyme concentration (;lysozymuria') indicates tubular proteinuria and therefore impaired tubular function, urinary lysozyme has been estimated in acute disorders where transient disturbances of renal function might be expected, in cases diagnosed clinically as extrarenal uraemia, and in a few examples of acute renal disease. Reversible lysozymuria occ...

Renal homotransplantation was performed in 185 patients between March 1962 and April 1968. None of the recipients, who were aged 3 to 55 years, had known liver disease prior to transplantation, although in 39 of the earlier cases adequate biochemical tests were not obtained preoperatively to establish this fact. In the other 146, hepatic function was studied before operation and at frequent int...

Introduction: Burden of disease in case of renal disorders is a proverbial ice-berg where very little is manifested and a lot remains undiagnosed. The patients present to a nephrologist when it is too late. In this context epidemiological studies are important to understand and treat renal diseases. This study was undertaken over a period of ten years at a tertiary care centre at Allahabad (Ind...

The kidney plays a key role in the maintenance of normal magnesium balance. The distal tubule of the kidney, namely the thick ascending limb of the loop of Henle and the distal convoluted tubule, is crucial for the regulation of serum magnesium levels and body magnesium content. The identification of molecular defects related to rare inherited magnesium losing disorders has contributed greatly ...

BACKGROUND Increased cancer incidence, particularly lymphoproliferative disease, is a complication of immunosuppression in organ transplantation. Non-Hodgkin's lymphomas (NHLs) occur frequently during the first year after transplantation, more so in North America than in Europe. METHODS This study audited and correlated the demographic, clinical, pathological, and outcome features of post-tra...

At the early stage of chronic kidney disease (CKD), the systemic mineral metabolism and bone composition start to change. This alteration is known as chronic kidney disease-mineral bone disorder (CKD-MBD). It is well known that the bone turnover disorder is the most common complication of CKD-MBD. Besides, CKD patients usually suffer from vascular calcification (VC), which is highly associated ...