OBJECTIVE Identify prognostic factors related to mortality and non-recovery of renal function. METHODS A prospective single-center study was conducted at the intensive care medicine department of a university hospital between 2012 and 2015. Patients with acute kidney injury receiving continuous renal replacement therapy were included in the study. Clinical and analytical parameters were colle...

background: vitamin d (vit d) is linked to various conditions including musculoskeletal, metabolic and   cardiopulmonary diseases. however, it is not clear whether correction of vit d deficiency exerts any beneficial effect in patients with pulmonary hypertension. methods: this study was a prospective uncontrolled longitudinal study. patients with pulmonary hypertension and vit d deficiency wer...

adrenal insufficiency is a life-threatening disorder which must be treated with glucocorticoid replacement and needs permanent dose adjustment during patient's different somatic situations. insufficient glucocorticoid doses result in adrenal crisis and must be treated with intravenous hydrocortisone. the patient was known with adrenal insufficiency and was treated optimally with fludrocortisone...

background : postmenopausal hot flash is a common disease amongst women with high prevalence of 75%. hormone replacement therapy (hrt) is a well-known relief of symptoms which has disadvantages such as side effects and contraindication for certain types of hormone related diseases and breast or estrogen related cancers. one of the alternatives is acupuncture which is an east asian and more spec...

BACKGROUND In the past 15 years, dramatic political and economic changes have occurred in Central and Eastern Europe (CEE) which also had a positive impact on the availability of renal replacement therapy. The aim of the present study was to analyse the progress achieved in the new millennium. METHODS Data from 18 CEE countries collected during two independent surveys (1999 and 2002) were val...

OBJECTIVE Continuous renal replacement therapy (CRRT) is a continuous process of bedside blood purification which is widely used in the treatment of acute kidney injury (AKI) and for fluid management. However, since AKI and fluid overload are often found to be associated with hemodynamic abnormalities, determining the relationship between CRRT and hemodynamics remains a challenge in the treatme...

BACKGROUND Acute kidney injury remains a common complication in critically ill patients and despite multiple trials and observational studies, the optimal timing for initiation of renal replacement therapy is still unclear. The early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury (ELAIN) study is a randomized, single-center, prospective, ...

AIMS To determine frequency, type, determinants, and outcome of malignancies in children with end stage renal failure. METHODS All Dutch patients, aged less than 15 years, who started chronic renal replacement therapy between 1972 and 1992 and who were at least 18 years old on 1 January 1997, were retrospectively studied. RESULTS Mean follow up from first renal replacement therapy was 15.5 ...

BACKGROUND Renal replacement therapy (RRT) has been implemented extensively in people to facilitate recovery from acute renal failure (ARF). RRT has not been explored in horses, but might provide a further treatment option in horses with ARF. OBJECTIVE To investigate efficacy and safety of RRT in horses. ANIMALS Five healthy adult horses. METHODS A prospective study was performed on horse...

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary disorder (estimated prevalence of 1 per 1000–1 2500 live births)1 characterized by development and growth multiple bilateral cysts eventually leading to end-stage renal replacement therapy.1