Transplantation of an organ harvested from another person is one of the methods of treatment of end-stage organ failure. Endothelial dysfunction is a frequent finding in transplant recipients. It is also very common in cardiovascular disorders and chronic kidney disease. Vascular adhesion protein-1 (VAP-1) is a dual-function glycoprotein. As an adhesion molecule, it is involved in rolling, adhe...

Hepatitis C infection is prevalent in candidates for and recipients of solid organ transplants. In the renal transplant population, HCV infection has been shown to decrease long-term patient and graft survival. The outcomes of HCV in recipients of other solid organ transplants are yet to be established and prospective studies will be needed in the future. In the absence of effective and safe an...

Human Cytomegalovirus (HCMV) represents the most common viral complication affecting solid organ transplant recipients (SOTRs) and its management is still debated. This study analyzes the association between HCMV infection and renal transplant recipients' outcomes. From January 2008 through December 2009, 97 consecutive renal transplant recipients were retrospectively studied. HCMV disease prev...

BACKGROUND Renal failure with following continuous renal replacement therapy is a major clinical problem in liver transplant recipients, with reported incidences of 3% to 20%. Little is known about the significance of postoperative acute renal failure or acute-on-chronic renal failure to postoperative outcome in liver transplant recipients. METHODS In this post hoc analysis we compared the mo...

BACKGROUND Anxiety and depression are the most common psychological disorders in kidney transplant recipients that may affect disease process and graft survival. OBJECTIVE Based on the types of kidney donation in our country, living vs. cadaveric donation, we conducted this study to compare psychological problems in renal recipients. METHODS This cross-sectional study was conducted on kidne...

hypertension is a common complication of kidney transplantation with the prevalence of 80%. studies in adults have shown a high prevalence of hypertension (htn) in the first three months of transplantation while this rate is reduced to 50- 60% at the end of the first year. htn remains as a major risk factor for cardiovascular diseases, lower graft survival rates and poor function of transplante...

INTRODUCTION African-American (AA) renal transplant recipients have a higher incidence of acute rejection when compared to Caucasian renal transplant recipients. This higher rejection rate holds true even with the addition of several of the newer immunosuppressive agents (e.g. mycophenolate mofetil (MMF) and Rapamycin). Acute rejection rates among Hispanic (H) renal transplant recipients are hi...

BACKGROUND AND OBJECTIVES Renal transplant recipients experience premature cardiovascular disease and death. The association of inflammation, all-cause mortality, and cardiovascular events in renal transplant recipients has not been examined in a large prospective controlled trial. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS ALERT was a randomized, double-blind, placebo-controlled study of ...