Kidney Transplantation in children is the treatment of choice to treat end stage renal disease. Improvements in immunosuppressive management have dramatically reduced the risk of early acute rejection and graft loss, however the long term results in terms of graft survival and morbidity still require search for new immunosuppressive regimens. Reducing of side effects are the challenges for impr...

We have used recombinant human erythropoietin (r-HuEPO) in children with chronic renal failure. There was significant improvement in anemia and wellbeing, along with regression of left ventricular mass and no change in the rate of decline of renal function. It is safe and effective in the pre-dialysis as well as the hemodialysis period. Considering the benefits of r-HuEPO, transplantation i...

Background and objective: Renal transplantation is an appropriate treatment for end stage renal disease and helps prolongation of patients survival with better quality, but immunosuppressive drugs that are used for inhibition of rejection after transplantation may cause some adverse effects in other organs such as the skin. Apparently, early recognition of those side effects and their app...

we have used recombinant human erythropoietin (r-huepo) in children with chronic renal failure. there was significant improvement in anemia and wellbeing, along with regression of left ventricular mass and no change in the rate of decline of renal function. it is safe and effective in the pre-dialysis as well as the hemodialysis period. considering the benefits of r-huepo, transplantation in ch...

kidney transplantation in children is the treatment of choice to treat end stage renal disease. improvements in immunosuppressive management have dramatically reduced the risk of early acute rejection and graft loss, however the long term results in terms of graft survival and morbidity still require search for new immunosuppressive regimens. reducing of side effects are the challenges for impr...

Background: The incidence of ischemic reperfusion injury (IRI) in early phase post-transplantation and activation of toll-like receptor (TLR-2) and TLR-4 remarkably impact the outcome of a renal allograft. Objective: To investigate whether the expression of TLRs in peripheral blood mononuclear cells (PBMCs) can predict the clinical outcome of kidney allografts. Methods: We obtained blood sample...

Objective: To compare the Spectral-Domain Optic Coherence Tomography (SD-OCT) findings of chronic renal failure (CRF) and transplant (RTx) patients.
 Methods: Sixty eyes thirty patients with CRF 60 RTx were enrolled in study. A thorough ophthalmologic examination was applied to each patient, including following parameters: best-corrected visual acuity (BCVA), intraocular pressure (IOP), an...

Background an objective: Renal transplantation may be considered as the only effective long-term therapy for chronic renal failure. Better surgical techniques and recent advances in immunosuppressive therapy allows patients to survive for many years. However, cutaneous lesions (Cosmetic, infectious, pre-cancerous and neoplastic) can be a significant problem for this group of patients. This stud...

oral mucosa can be affected in many systemic diseases such as chronic renal failure (crf). many metabolic and hematologic disorders develop in patients with crf which can also affect oral cavity. oral mucosa, teeth, salivary glands and jaw bones are affected. although hemodialysis can improve many of systemic features but the best treatment is renal transplantation. in addition to previous feat...