The cellular and physiologic mechanisms that regulate the resolution of inflammation remain poorly defined despite their widespread importance in improving inflammatory disease outcomes. We studied the resolution of two cardinal signs of inflammation-pain and swelling-by investigating molecular mechanisms that regulate neural and lymphatic vessel remodeling during the resolution of corneal infl...

OBJECTIVE To develop a novel method for rapid myocardial T1 mapping at high spatial resolution. METHODS The proposed strategy represents a single-shot inversion recovery experiment triggered to early diastole during a brief breath-hold. The measurement combines an adiabatic inversion pulse with a real-time readout by highly undersampled radial FLASH, iterative image reconstruction and T1 fitt...

Background The border zone of myocardial scar after myocardial infarction (MI) plays an important role for arrhythmia formation. For this reason, high-resolution 3D information of scar tissue for planning of electrophysiological interventions after MI is highly desirable. This study evaluates sharpness of the borders (SB) of scar after MI by a self-navigated isotropic 3D free-breathing wholehea...

Numerous studies have shown that being able to resolve and recover from conflicts is of key importance for relationship satisfaction and stability in adults. Less is known about the importance of these relationship dynamics in adolescent romantic relationships. Therefore, this study investigated whether conflict resolution and recovery predict breakups in middle adolescent couples. Couples who ...

Super-resolution theory aims to estimate the discrete components lying in a continuous space that constitute a sparse signal with optimal precision. This work investigates the potential of recent super-resolution techniques for spectral estimation in multirate sampling systems. It is shown in the first part of this paper that, under the existence of a common supporting grid, the joint frequency...

Addiction recovery mutual aid societies have played a significant role in the resolution of severe alcohol and other drug problems throughout the world and have exerted a particularly profound influence on the professional treatment of addiction (Humphreys, 2004; White, 2004). The purpose of this article is to discuss five current contextual influences that will influence the future of Alcoholi...

Template-guided transperineal aspiration is a minimally invasive treatment option for patients with Mullerian duct cysts. The precise targeting provided by the brachytherapy template grid enables specific targeting, quick recovery and resolution of symptoms without complications.

This paper studied PET intrinsic spatial resolution and contrast recovery improvement for PET/MRI dual modality systems. A Monte Carlo simulation tool was developed to study positron diffusion in tissues with and without a magnetic field for six commonly used isotopes ((18)F, (11)C, (13)N, (15)O, (68)Ga and (82)Rb). A convolution process was implemented to investigate PET intrinsic spatial reso...

Acute lung injury (ALI) is characterized by rapid alveolar injury, inflammation, cytokine induction, and neutrophil accumulation. Although early events in the pathogenesis of ALI have been defined, the mechanisms underlying resolution are unknown. As a model of ALI, we administered intratracheal (i.t.) LPS to mice and observed peak lung injury 4 days after the challenge, with resolution by day ...

A critical component of disaster recovery planning is testing, which involves verification of the effectiveness of the DR solutions. Currently, there are several limitations that plagues disaster testing efforts such as the inability to create realistic disaster scenarios and test them in a production environment. Cyber Range Concept of Operations (CONOPS) presents an opportunity for overcoming...