Background Pulmonary involvement is the main cause of mortality in cystic fibrosis (CF). Airway clearance techniques are non-pharmacological complement options for CF patients. The aim of this study was to evaluate the short-term outcome of airway cleaning treatment in patients with cystic fibrosis in a children's hospital. Materials and Methods This clinical trial study conducted on 40 CF pati...

OBJECTIVE To analyze the shuttle walk test, and its respective retest, comparing children with cystic fibrosis (CF) to normal children. METHODS The children were divided into two groups: the CF group, composed of children in whom the diagnosis had been confirmed through sweat testing; and the control group, composed of normal children with no history of pulmonary diseases and no alterations i...

Cystic fibrosis (CF) is the most common severe autosomal recessive disorder caused by a wide spectrum of mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The frequencies, types and distributions of mutations vary widely between different populations and ethnic groups. The aim of this study was to perform a comprehensive analysis of the C...

Five common range forage including Agropyron intermedium, Bromustomentellus, Hordeum bulbosum, Cousinia bakhtiarica and Scariolla orientalis, weresampled during three phenological stages, from controlled rangeland stations over fivelocations in Chaharmahal and Bakhtiari province, Iran. All samples were chemicallyanalyzed for Crude Protein (CP%), in vitro Dry Matter Digestibility (DMD), OrganicM...

In this research, the effect of different biopolymers such as polyethylene glycol (PEG) and polyvinylalcohol (PVA) on synthesis and characterization of polymer/cobalt ferrite (CF) nano-composites bymechanical alloying method has been systematically investigated. The structural, morphological andmagnetic properties changes during mechanical milling were investigated by X-ray diffraction (XRD),Fo...

The first successful heart-lung and lung transplant operations in cystic fibrosis (CF) patients were performed in 1983 and 1987, respectively. Lung transplantation is now available at dozens of centers in North America, Europe, and Australia. Recent technical developments and the major limitations of donor organ availability prompted the CF Foundation to sponsor a meeting of 37 experts to evalu...

Airway inflammation, one of the major factors leading to lung damage in cystic fibrosis (CF) patients, is associated with an abnormal increase in proinflammatory cytokines. In this work, we demonstrate the increased release of the proinflammatory cytokines after lipopolysaccharide (LPS) stimulation: human interleukin (hIL)-8 in CF and non-CF airway xenografts, and hIL-6 and human growth-related...

In this work, a simple, rapid and cost-effective method for the simultaneous quantification of two major γ-oryzanol components in agriproducts was established by silica solid-phase extraction (SPE) coupled with UHPLC–MS/MS. Silica SPE sorbents consist unbonded gel high polarity can retain most analytes acidic properties. are materials that be prepared simply without large volume toxic chlorinat...

Background and Objective It is unclear whether early morphological change (EMC) is a predictive marker for regorafenib in metastatic colorectal cancer (mCRC). Therefore, the present study investigated whether EMC can predict the outcome of mCRC patients receiving regorafenib. Results This study evaluated 68 patients. Among 52 patients with lung metastasis, 16 (31%) had cavity formation (CF). ...

BACKGROUND Primary ciliary dyskinesia (PCD) is associated with chronic airway inflammation resulting in bronchiectasis. METHODS The levels of exhaled nitric oxide (eNO), carbon monoxide (eCO) and nasal NO (nNO) from bronchiectatic patients with PCD (n=14) were compared with those from patients with non-PCD bronchiectasis without (n=31) and with cystic fibrosis (CF) (n=20) and from normal subj...