http://bmj.com/cgi/content/full/330/7486/299 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/330/7486/299#BIBL This article cites 15 articles, 7 of which can be accessed free at: Rapid responses http://bmj.com/cgi/eletter-submit/330/7486/299 You can respond to this article at: http://bmj.com/cgi/content/full/330/7486/299#responses free...

Shifting the sowing time of chickpea plants from spring to autumn in arid and semi-arid regions Iran is unavoidable. To study feasibility this issue, 32 desi-type genotypes were planted Mashhad (as a temperate region) Jolgeh Rokh cold screen cold-tolerant genotypes. The results revealed that 100% 19% had survival range 76–100%. MCC918 MCC913 highest height (69 33 cm, respectively). biological y...

The effect of γ-radiation dosage on the thermal stability cross-linked acrylic polymer "Carbomer-140" (СRB) was investigated. DTA, TGA, and DTG curves show multistage processes occurring in different temperature ranges heating CRB from 25 °C to 500 °C. rates decomposition were determined 40–110 °C, 180–260 260–330 330–500 In combination with results electronic structure calculations, potential ...

OBJECTIVE We investigated the influence of elevated homocysteine plasma levels and 2 polymorphisms, 677C/T and 1298A/C, of the methylenetetrahydrofolate reductase (MTHFR) gene on the risk of restenosis after stenting in patients with symptomatic coronary artery disease. METHODS AND RESULTS Homocysteine levels and MTHFR genotypes were determined in 800 consecutive patients treated with coronar...

http://bmj.com/cgi/content/full/330/7487/347 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/330/7487/347/DC1 "References w1 w29" References http://bmj.com/cgi/content/full/330/7487/347#BIBL This article cites 20 articles, 8 of which can be accessed free at: Rapid responses http://bmj.com/cgi/eletter-submit/330/7487/347 You can re...

PURPOSE Despite the advent of FDA-approved therapeutics to a limited number of available targets (kinases and mTOR), PFS of kidney cancer (RCC) has been extended only one to two years due to the development of drug resistance. Here, we evaluate a novel therapeutic for RCC which targets the exportin-1 (XPO1) inhibitor. MATERIALS AND METHODS RCC cells were treated with the orally available XPO1...

MicroRNAs have recently emerged as key regulators of cancers. This study was therefore conducted to investigate the role of miR-330 in biological behaviors of human glioblastoma U87 and U251 cell lines and its molecular mechanism. SH3GL2 gene was identified as the target of miR-330. MiR-330 overexpression was established by transfecting miR-330 precursor into U87 and U251 cells, and its effects...

microRNAs (miRNAs), small non-coding RNAs, have emerged as key regulators of a large number of genes. The present study aimed to explore novel biological functions of miR-330 in the human prostate cancer cell lines DU145 and PC3. We confirmed that miR-330 was downregulated and inversely correlated with specificity protein 1 (Sp1) expression. Overexpression of miR-330 by transfection of a chemic...

BACKGROUND Tumor necrosis factor superfamily (TNFSF) proteins are involved in the genesis of inflammatory bowel disease (IBD). We examined the association of seven single nucleotide polymorphisms (SNP) in the TNFSF15 gene with Crohn's disease (CD) and ulcerative colitis (UC) in the Indian population. METHODS Seven SNPs in the TNFSF15 gene (rs10114470, rs3810936, rs6478108, rs4263839, rs647810...