BACKGROUND A lung-protecting strategy is essential when ventilating acute lung injury/acute respiratory distress syndrome patients. Current emphasis is on limiting inspiratory pressure and volume. This study was designed to investigate the effect of peak inspiratory flow on lung injury. METHODS Twenty-four rabbits were anesthetized, tracheostomized, ventilated with a Siemens Servo 300, and ra...

TAYLOR, c. R. Metabolism, respiratory changes, and water balance of ~12 antelope, the eland. Am. J, Physiol. 217(l) : 3 17-320. 1969. The eland is a large East African antelope which can survive prolonged droughts in hot semideserts without drinking. This ability is partly due to a low respiratory water loss relative to the oxygen consumption at night. Each night the eland has a low body temper...

Bendjelid, Karim, Peter M. Suter, and Jacques A. Romand. The respiratory change in preejection period: a new method to predict fluid responsiveness. J Appl Physiol 96: 337–342, 2004; 10.1152/ japplphysiol.00435.2003.—The accuracy and clinical utility of preload indexes as bedside indicators of fluid responsiveness in patients after cardiac surgery is controversial. This study evaluates whether ...

Kuebler WM, Mertens M, Pries AR. A two-component simulation model to teach respiratory mechanics. Adv Physiol Educ 31: 218–222, 2007; doi:10.1152/advan.00001.2007.—Interactive learning has been proven instrumental for the understanding of complex systems where the interaction of interdependent components is hard to envision. Due to the mechanical properties and mutual coupling of the lung and t...

background: pulmonary complications, respiratory symptoms and depression are common occurrences which contribute to the morbidity and mortality seen in individuals living with hiv/aids. this study investigated the effect of aerobic exercise on the pulmonary functions, respiratory symptoms and psychological status of people living with hiv. methods: this study was conducted in lagos, nigeria fro...

Estenne M. Effect of lung transplant and volume reduction surgery on respiratory muscle function. J Appl Physiol 107: 977–986, 2009; doi:10.1152/japplphysiol.91620.2008.—Lung transplantation and lung volume reduction surgery have opened a new therapeutic era for patients with advanced emphysema. In addition to providing impressive clinical benefits, they have helped us better understand how the...

Bendjelid, Karim, Peter M. Suter, and Jacques A. Romand. The respiratory change in preejection period: a new method to predict fluid responsiveness. J Appl Physiol 96: 337–342, 2004; 10.1152/ japplphysiol.00435.2003.—The accuracy and clinical utility of preload indexes as bedside indicators of fluid responsiveness in patients after cardiac surgery is controversial. This study evaluates whether ...

BACKGROUND Endotracheal suctioning is required but can have adverse effects, and could affect cardiorespiratory variables that are used to predict whether the patient is ready for extubation. METHODS In a prospective cohort study in a university hospital's medical intensive care unit, we measured the impact of closed-system suctioning on cardiopulmonary variables in spontaneously breathing pa...

BACKGROUND There have been limited comparative data regarding the investigations on pulmonary and respiratory muscle function in the patients with different parkinsonism disorders such as Parkinson's disease (PD) and multiple system atrophy (MSA) versus normal elderly. The present study is aiming to characterize the performance of pulmonary function and respiratory muscle strength in PD and MSA...

BACKGROUND Increased respiratory rate (tachypnea) is frequently observed as a clinical sign of influenza pneumonia in pediatric patients admitted to the hospital. We previously demonstrated that influenza infection of adult cotton rats (Sigmodon hispidus) also results in tachypnea and wanted to establish whether this clinical sign was observed in infected infant cotton rats. We hypothesized tha...