Familial adenomatous polyposis (FAP) is a dominantly inherited condition caused by germline mutation of the APC gene resulting in formation of numerous large bowel adenomas in late childhood or adolescence. Unless these are removed, colorectal cancer inevitably develops. Prophylactic surgical treatment is required to prevent this. In surgical decision making, considerations should include genot...

INTRODUCTION Surgery is the only treatment option for familial adenomatous polyposis (FAP). Aim of surgery in FAP is to minimize colorectal cancer risk without need for permanent stoma. There are especially two operation options; Total colectomy with ileorectal anastomosis (IRA) and total proctocolectomy with ileo-pouch anal anastomosis (IPAA). We report here a patient with FAP who had resectio...

A seeded fistula-in-ano from a synchronous sigmoid colon cancer is rare. The literature is still divided regarding the standard treatment, although an abdominoperineal resection is considered the best option when curative resection is possible. This case is distinct from previous reports, as the patient had known metastatic liver disease before surgery, and proceeded with a pan-proctocolectomy ...

There have been rapid advances in medical and surgical therapy for ulcerative colitis (UC), including the widespread use of immuno­ modulators and biological agents, and routine application of restorative procto colectomy. Restorative proctocolectomy with ileal pouch– anal anastomosis (IPAA) has become the sur­ gical treatment of choice for patients with medically refractory UC or colitis­assoc...

We read with interest the article by Eshuis et al., ‘Previous infliximab therapy and postoperative complications after proctocolectomy with ileum pouch anal anastomosis’.1 The authors conducted a retrospective study evaluating patients who underwent pouch surgery for ulcerative colitis (UC). One-stage procedures (n=33; proctocolectomy with pouch, with or without temporary diversion) and two-sta...

A case of adenocarcinoma arising in a 39-year-old patient after restorative proctocolectomy is reported. The patient underwent an ileal pouch-anal anastomosis with double-stapled technique for severe ulcerative colitis 18 years earlier, without evidence of associated neoplasm or dysplasia in operative specimen. After endoscopic diagnosis of adenocarcinoma, the patient was submitted to excision ...