Glaucoma is characterized by a combination of structural changes in the retina and optic nerve head and functional perimetric damage. Examination and documentation of the retinal nerve fiber layer are essential for the diagnosis and monitoring of glaucoma. Spectral domain Optical coherence tomography (OCT) is a high resolution imaging device capable of obtaining reproducible retinal nerve fiber...

This study identifies clinical vision measures or retinal structural measures associated with the driving performance of diabetic retinopathy patients. Twenty-five licensed drivers with diabetic retinopathy (median age, 53 years; range, 34-72 years) completed clinical tests (visual acuity, letter contrast sensitivity, and Humphrey 30-2 visual fields) and structural examinations (retinal thickne...

PURPOSE We determine whether the automated segmentation software, Duke Optical Coherence Tomography Retinal Analysis Program (DOCTRAP), can measure, in a platform-independent manner, retinal thickness on Cirrus and Spectralis spectral domain optical coherence tomography (SD-OCT) images in eyes with diabetic macular edema (DME) under treatment in a clinical trial. METHODS Automatic segmentatio...

Purpose To report the spectral domain optical coherence tomography (SD-OCT) features of a focal retinitis in an elderly male patient with bilateral syphilitic panuveitis. Observations In the left eye (LE), spectral domain SD-OCT images during the active period revealed hyperreflectivity extending through the full thickness of the retina with no individualization of the layers, except for the ...

PURPOSE To report the findings in three cases in which the average foveal thickness was increased after a thin epiretinal membrane (ERM) was removed by vitrectomy with internal limiting membrane (ILM) peeling. METHODS The foveal contour was normal preoperatively in all eyes. All cases underwent successful phacovitrectomy with ILM peeling for a thin ERM. The optical coherence tomography (OCT) ...

PURPOSE It is known that symptoms of congenital achromatopsia are caused by the lack of functioning cones, but there are very few published data on histologic changes in the retina in these cases. This study was conducted to examine in vivo the anatomic structure of the retina of patients with achromatopsia. METHODS Fifteen eyes of eight patients with congenital achromatopsia and 18 eyes of n...

purpose: to evaluate the correlation between retinal nerve fiber layer (nfl) thickness and visual field parameters in patients with optic atrophy. methods: this study was performed on 35 eyes of 28 patients with optic atrophy. nfl thickness was measured by optic coherence tomography (oct) and visual field analysis was performed by humphrey perimetry. the correlation between nfl thickness and vi...

AIM To evaluate the correlation of the retinal blood vessel position and the retinal nerve fibre layer (RNFL) thickness profile. METHODS RNFL thickness of 81 healthy subjects was measured using scanning laser polarimetry (SLP). To quantify the retinal blood vessel position, the angle (superior and inferior) between a horizontal line and a line from the optic disc centre to the intersection of...

BACKGROUND/OBJECTIVE In addition to cirrhosis of the liver, Wilson's disease leads to copper accumulation and widespread degeneration of the nervous system. Delayed visual evoked potentials (VEPs) suggest changes to the visual system and potential structural changes of the retina. METHODS We used the latest generation of spectral domain optical coherence tomography to assess the retinal morph...

Purpose To describe changes in the retina and choroidal flow by optical coherence tomography angiography (OCT-A) after a single dose of oral sildenafil. Method A case-control study. Patients in the study group received 50 mg of oral sildenafil. Patients in the control group received a sham pill. Retinal and choroidal images were obtained at baseline (before pill ingestion) and 1 hour after in...