The Pyrrhonic Sceptics in ancient Greece employed a useful catchword, epoche ('suspension of judgment'), in philosophic argument.' The expression serves admirably to summarise the current state of knowledge concerning the unique retinopathy that affects prematurely born infants. There are renewed, intense debates about pathophysiological mechanisms that may lead to retinopathy of prematurity, a...

Introduction Retinopathy of prematurity (ROP) was originally designated as retrolental fibroplasias by Terry in 1952 who related it with premature birth. Term ROP was coined by Heath in 1951. It is a disorder of development of retinal blood vessels in premature babies. Normal retinal vascularization happens centrifugally from optic disc to ora. Vascularization up to nasal ora is completed by 8 ...

as noted by organization of the vitreous overlying the optic nerve presumedly resulted in macular detachment and visual loss. Plasminassisted vitrectomy was successful in reestablishing the patient’s normal macular anatomy and restoring her baseline visual acuity. When present and confirmed by careful clinical examination, including adjunct methods such as optical coherence tomography, subclini...

as noted by organization of the vitreous overlying the optic nerve presumedly resulted in macular detachment and visual loss. Plasminassisted vitrectomy was successful in reestablishing the patient’s normal macular anatomy and restoring her baseline visual acuity. When present and confirmed by careful clinical examination, including adjunct methods such as optical coherence tomography, subclini...

We screened 50 neonates fulfilling the inclusion criteria admitted during the study period in a teaching hospital in a north-eastern state of India. Out of 50 neonates screened, 22 (44%) developed retinopathy of prematurity. There was significant association between the birth weight and gestational age of the baby at the time of the delivery with the development of ROP. Multivariate analysis of...

OBJECTIVES To investigate the incidence, severity and risk factors of retinopathy of prematurity (ROP) in triplets. MATERIALS AND METHODS The medical records of consecutive premature triplets who had been screened for ROP in a single maternity hospital were analyzed and presence and severity of ROP; birth weight, gender, gestational age of the infant; route of delivery and the mode of concept...

The demise of retinopathy of prematurity (ROP) was confidently forecast in the 1950s when supplemental oxygen was identified as a causal factor. Unfortunately this did not transpire and by the mid-1960s it became all too apparent that ROP was not solely of historical interest. The purpose of this article is to consider screening for ROP working on the basis that at present this condition is not...

There have been many major advances recently that have improved the identification and management of retinopathy of prematurity (ROP). This chapter describes the clinical features of ROP and then considers briefly the incidence and epidemiology of acute phase disease. This is followed by a discussion of the two ROP epidemics and ROP-induced disability in high, low and middle income countries, a...

Since the publication in 1981 of an overview of our previous 15 years' research into the genesis of the retinopathy of prematurity, the incidence of this disease has continued to rise as the survival rates of increasingly premature infants have risen. Since then, we have completed a study of the morphology of the developing retinal vasculature that lends support to the hypothesis described in t...