SUMMARY Hepatitis B Virus is one of the most important and common infections agent in the world and is prohably endemic in IRAN. In our study the 12 years prevalance (April 1981-December 1993) HBsAg and VDRL positive cases and their relationship with some epidemiologic factors such as sex, age, occupation among the blood donors of the Ramadan province (west of IRAN) have been considered. ...

The Rh blood group system discovered in 1939 is only second in importance to the ABO system in terms of transfusion [1]. It is a highly complex blood group system with more than fifty different antigens [2]. However, most clinical transfusion issues are associated with the five principal antigens D, C, c, E and e. Rh antigens are non-glycosylated proteins in the RBC membrane [3]. Two closely li...

The Rh blood group system discovered in 1939 is only second in importance to the ABO system in terms of transfusion [1]. It is a highly complex blood group system with more than fifty different antigens [2]. However, most clinical transfusion issues are associated with the five principal antigens D, C, c, E and e. Rh antigens are non-glycosylated proteins in the RBC membrane [3]. Two closely li...

On human (Homo sapiens) chromosome 1, there is a tandem duplication encompassing Rh blood group genes (Hosa_RHD and Hosa_RHCE). This duplication occurred in the common ancestor of humans, chimpanzees (Pan troglodytes), and gorillas, after splitting from their common ancestor with orangutans. Although several studies have been conducted on ape Rh blood group genes, the clear genome structures of...

Rh (rhesus) D is the dominant antigen of the Rh blood group system. Recent advances in characterization of the nucleotide sequence of the cDNA(s) encoding the Rh D polypeptide allow the determination of the Rh D genotype at the DNA level. This can be of help in cases in which red blood cells are not available for phenotyping, eg, when in concerns a fetus. We have tested three independent DNA ty...

BACKGROUND Despite a recent American Heart Association (AHA) consensus statement emphasizing the importance of resistant hypertension (RH), its control is still a challenge for conventional medicine. The Chinese herbal formula, Qutan Huayu Fang, has been used effectively to assist antihypertensive agents in blood pressure control, but its effect for RH patients is still unclear. This pilot stud...

BACKGROUND Abnormal haemoglobin variants (HbSS,AS,AC,SC,etc) have been known to be common among blacks. Patients with sickle cell disease are often faced with the risk of alloimmunization from allogeneic blood transfusion. OBJECTIVES The study was designed to sample students population of African descents for the purpose of updating information on the prevalence of abnormal haemoglobin varian...

OBJECTIVES To investigate clinical characteristics, target organ damage, and the associated risk factors of the patients aged ≥ 80 years with true resistant hypertension (RH). METHODS Patients aged ≥ 80 years with hypertension (n = 1163) were included in this study. The included participants attended a structured clinical examination and an evaluation of RH was carried out. The prevalence, cl...

It has been shown that the Rhesus (Rh) blood group antigens are encoded by two homologous genes: the Rh D gene and the Rh CcEe gene. The Rh CcEe gene encodes different peptides: the Rh C, c, E, and e polypeptides. Only one nucleotide difference has been found between the alleles encoding the Rh E and the Rh e antigen polypeptides. It is a C -+ G transition at nucleotide position 676, which lead...