We report the case of a 44-year-old man who experienced a fatal and untreatable delayed vasospasm after resection of a recurrent temporal IV grade primitive neuroectodermal tumor (PNET). The histological analysis demonstrated a rare rhabdoid variant of the tumor with a diffuse myxoid degeneration; molecular investigations demonstrated an upregulation of IL-1β and IL-6 expression in the recurren...

We report a case of atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system (CNS) in an adult and its immunological phenotype and chromosomal DNA imbalance characteristics, as detected by comparative genomic hybridization (CGH). The immunohistochemical characteristics showed that atypical rhabdoid cells were positive for epithelial membrane antigen, vimentin, desmin, and glial fi...

In this article, we present a rare case of renal pelvic carcinoma. The imaging examination of a 75-year-old Japanese man disclosed the left renal pelvic tumor. The histological examination showed the finding of predominant undifferentiated discohesive mononuclear cells with abundant osteoclast-like giant cells and a minor component of papillary urothelial carcinoma. Rhabdoid morphology was foca...

Malignant rhabdoid tumor (MRT) is a rare and aggressive malignancy associated with poor outcomes. MRT of the liver is even rarer, and little information has been described. We report the case of an 8-month-old boy with MRT of the liver. The tumor showed aggressive progression despite a multidisciplinary approach, and the patient died due to multiple organ failure 14 days after admission. Autops...

Renal tumors other than Wilms’ tumor are infrequent in childhood. Wilms’ tumors account for 6% to 7% of childhood cancer, whereas the remaining renal tumors account for less than l%.27 The most common nonWilms‘ tumors are clear cell sarcoma of the kidney, rhabdoid tumor of the kidney (both formerly considered unfavorable Wilms’ tumor variants but now considered separate tumors), renal cell carc...

We present a 51 year old female patient with a pelvic desmoplastic small round cell tumor with an unusual immunohistochemical profile, including absence of significant cytokeratin expression, complete negativity for desmin and widespread loss of nuclear INI-1 expression (>90% of tumor cells). The neoplastic cells were positive for epithelial membrane antigen (EMA), vimentin, and WT-1 (antibody ...