reductase inhibitors are the most widely used drug for the treatment of hyperlipidemias but their long term use is associated with rhabdomyolysis. Administration of simvastatin (80 mg/kg, p.o.) and gemfibrozil (600mg/kg, p.o. twice) for 30 days produced significant increase in the level of various serum parameters (creatine Phospho kinase, urea and blood urea nitrogen) indicating development of...

A 15-year-old athletic male was hospitalized with back pain and myalgia after standing out in the cold weather watching a soccer match. Hewas passing dark red urine on admission. He took no prescribed or illicit medications. Family history and physical examination was unremarkable. Laboratory analysis revealed a creatine kinase of 113 542 U/L and normal renal function. A diagnosis of rhabdomyol...

V. Jain A.N. Ellingson W.R.K. Smoker SUMMARY: We report a case of rhabdomyolysis due to acetaminophen overdose involving the lateral pterygoid muscles bilaterally, in addition to the other muscles of the abdomen and pelvis. To the best of our knowledge, involvement of the head and neck muscles by rhabdomyolysis has not been reported previously. The isolated involvement of the lateral pterygoid ...

A case is reported of a 39-year-old woman with recurrent rhabdomyolysis caused by minor S. pyogenes tonsillitis. She was diagnosed with the adult form of CPT-II deficiency. Molecular analysis revealed compound heterozygosity for a common c.338C > T (p.Ser113Leu) mutation in exon 3 and a most likely pathogenic c.200C > G (p.Ala67Gly) variant in exon 2. Here we discuss the case, along with a clin...

Rhabdomyolysis ranges from an asymptomatic illness with elevation in the creatine kinase level to a life-threatening condition associated with extreme elevations in creatine kinase, electrolyte imbalances, acute renal failure and disseminated intravascular coagulation. Muscular trauma is the most common cause of rhabdomyolysis. Less common causes include muscle enzyme deficiencies, electrolyte ...

This case report details the onset of masseter muscle rigidity, elevated creatine kinase levels, and rhabdomyolysis following a sevoflurane mask induction and succinylcholine administration in a 12-year-old boy. The patient had no family or personal history of neuromuscular disease or malignant hyperthermia. Hyperkalemia, metabolic acidosis, and rhabdomyolysis occurred within 75 minutes of mass...

UNLABELLED The association of diabetes insipidus and adipsia after craniopharyngioma surgery has high morbidity. Hypernatremia can be caused by adipsia and be aggravated by diabetes insipidus. Rhabdomyolysis rarely occurs. CASE REPORT This is the first report of a diabetic patient with craniopharyngioma who developed diabetes insipidus and adipsia after surgery, evolving with severe hypernatr...

Rhabdomyolysis is an acute life-threatening condition that can occur in childhood secondary to many causes. The authors report the case of a 3-year-old male child who presented with acute rhabdomyolysis. The peak plasma creatine kinase level was extremely high. The 2 main causes of rhabdomyolysis in childhood are viral myositis and trauma, which can sometimes lead to acute renal failure. The hi...

A 64-year-old Japanese man with multiple myeloma was admitted to our institute due to fever and hypotension. He had received multiple courses of chemotherapy just before his febrile episode. Blood culturing detected Morganella morganii. At the time of the diagnosis, his laboratory findings revealed massive rhabdomyolysis with a significantly increased creatinine kinase level (CK; 3,582 U/L); 98...

Brucine is the predominant alkaloid present in the bark of the tree Strychnos nux vomica and is a weaker alkaloid when compared to strychnine. However, its toxicological property is akin to strychnine. We report a rare case of brucine poisoning complicated by acute renal failure and rhabdomyolysis. A 24-year-old male presented with a history of consumption of a decoction made from the bark of t...