Jens-S. Vöckler1 Gaurang Mehta1 Yong Zhao2 Ewa Deelman1 Mike Wilde3 1University of Southern California Information Sciences Institute 4676 Admiralty Way Ste 1001 Marina Del Rey, CA 90292 {jens,gmehta,deelman} at isi dot edu 2University of Chicago Dept. of Comp. Science 1100 East 58th Street Chicago, IL 60637 yongzh at cs dot uchicago dot edu 3Argonne National Laboratories Math. and Comp. Sci. D...

Rhapontigenin was produced from rhapontin isolated from a methanol extract of Rheum undulatum roots by enzymatic transformation. Rhapontin and rhapontigenin exhibited dose-dependent inhibition of tyrosinase activity and melanin synthesis in B16F10 melanoma cells, but the inhibitory activity of rhapontigenin was greater than that of rhapontin. Thus the bioconversion of rhapontin enhanced its abi...

A dry extract from the roots of rhapontic rhubarb (extract Rheum rhaponticum (L.); ERr) has been commercially available in Germany for over two decades to treat menopausal symptoms. However, the molecular basis of its clinical effectiveness remains obscure. This article reviews the in vitro and in vivo data of its estrogenic actions, particularly those mediated by estrogen receptor-beta (ERbeta).

.uk/njrcentre/Default.aspx 4 Franklin J, Ingvarsson T, Englund M, Lohmander LS. Sex differences in the association between BMI and total hip or total knee joint replacement resulting from osteoarthritis. Ann Rheum Dis 2009; 68: 536–40 5 Memtsoudis SG, Sun X, Chiu Y,et al. Perioperative comparative effectiveness of anesthetic technique in orthopedic patients. Anaesthesiology 2013; 118: 1046–58

Although acute symptoms recurred during treatment in seven of the cases on aspirin, there was no evidence of recrudescence in the phenylbutazone group. REFERENCES Ablard, G., Larcan, A., and Welfringer, A. (1957). Un. m'd. Can., 86, 932. Begg, T. B., Kerr, J. W., and Knowles, B. R. (1962). Brit. med. 7., 2, 223. Chaptal, J., Jean, R., and Campo, C. (1956). Sem. Hop. Paris, 32, 1175. Colson, J. ...

seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of rheum palmatem. their structures were identified as piceatannol(1), resveratrol(2), piceid(3), rhapontigenin(4), piceatannol-3'-o-β-d-glucopyranoside(5), rhaponticin(6), catechin(7) and desoxyrhapontigenin(8). anti-monoamine oxidase (mao) activities of compounds 1–8 were tested. compounds 1 and 8 showe...