rheumatoid arthritis is a chronic inflammatory disease characterized by the sequestration of various leukocyte subpopulations within both the developing pannus and synovial space. this study was undertaken to examine the therapeutic potency of tindurin in experimental rheumatoid arthritis. collagen-induced arthritis (cia) was induced by intradermally immunization of lewis rats at the base of th...

objective (s):rheumatoid arthritis (ra) is a chronic systemic inflammatory disorder, primarily targeting the synovium and articular cartilage that leads to joint damage. recent reports have suggested the role of adipocytokines in mediating joint damage; however it still is a matter of debate. the purpose of this study was to evaluate the association between serum values of adiopocytokines (lept...

honey bee sting is used in some societies as a treatment of inflammation in joint diseases such as arthritis. to investigate the effect of honey bee venom in reducing inflammation, we selected 30 male wister rats which were divided in to 6 groups. except group 1, all remaining groups received 0.5 ml of complete freund’s adjuvant to induce arthritis. after 9 days, all animals that received adjuv...

First published as ‘Colour Aids Rheumatology’ in 1984 and as ‘Rheumatology: Colour Guide’ in 1992 this small book and indeed the Colour Guides series seeks to confirm the old adage that, interalia, “...a picture paints a thousands words”. The book features clinical and imaging photographs of common rheumatological conditions ranging from rheumatoid arthritis to Reiter’s disease, and juvenile ch...

Background and Objectives: The cause and pathophysiology of rheumatoid arthritis has not been fully understood and an experimental model of this disease is essential for research on the problem. In this research study, establishment and histopathological changes of chronic arthritis due to intra-articula...

In the last years, new evidences of the relationship between immune system and bone have been accumulated both in animal models and in humans affected by bone disease, such as rheumatoid arthritis, bone metastasis, periodontitis, and osteoporosis. Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue with a subsequent increase in bone fragility and s...

INTRODUCTION Glucocorticoid (GC)-induced osteoporosis is a frequent complication in patients with rheumatoid arthritis. However, little information exists about the consequences of GC use in patients with early arthritis. Here we describe the variables underlying the use of GC in early arthritis, as well as its effect on bone-mineral density. METHODS Data from 116 patients in our early arthri...

conclusions due to the chronic nature of ra, promoting the qol and adherence to therapies could be achieved through convincing the patients. therefore, identification of weak points and planning for them at all levels; from individual to the community level is suggested. data extraction in the first step, the extracted results were summarized in the extraction table, and then analyzed using the...