Autoantibodies are proven useful diagnostic tools for a variety of rheumatic and non-rheumatic autoimmune disorders. However, a highly specific marker autoantibody for rheumatoid arthritis (RA) has not yet been determined. The presence of rheumatoid factors is currently used as a marker for RA. However, rheumatoid factors have modest specificity (~70%) for the disease. In recent years, several ...

Rheumatoid arthritis (RA) is a chronic systemic connective tissue disease with multiple organ impairment and unknown aetiology. Rheumatoid arthritis leads to activation of immune processes and formation of abnormal antibodies. They participate in antigen-antibody complexes and accumulate in various tissues (mainly in synovial tissue). The removal of circulating complexes through plasmapheresis ...

We encountered the rare case of a 48-year-old Caucasian woman who developed Takayasu arteritis (TA) while suffering from seropositive rheumatoid arthritis (RA). Several studies have reported an association between TA and various autoimmune disorders, however, the concurrent presence of Takayasu arteritis and rheumatoid arthritis is described in only few cases in the literature to date. The exac...

Patients with rheumatoid arthritis (RA), 500 men and 500 women, aged 40 years and over, together with a control population matched by age and sex, were observed over a 10 year period. The overall mortality was significantly higher in both men and women with rheumatoid arthritis than in the controls due to an excess mortality from infections and cardiovascular and renal diseases. During the foll...

Rheumatoid arthritis (RA) is a chronic condition which major contributor to disability in older adults. The cornerstone of rheumatoid care now disease-modifying antirheumatic medication. most widely used medication among these hydroxychloroquine, has been shown have antioxidant properties and delay the course illness. Thus, current study's objective compare oxidant status RA patients Mosul ...

Biological agents are widely used for various immune-mediated diseases, with remarkable effectiveness in the treatment of rheumatoid arthritis (RA), psoriasis, psoriatic arthritis, ankylosing spondylitis and Crohn's disease. However, attention needs to be drawn to the adverse effects of these therapies and the risk of reactivating underlying granulomatous infectious diseases such as tuberculosi...

The incidence of rheumatoid arthritis (RA) has been reported to be correlated with a disorder of immunregulation. Rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs) play an important role in regulating the local immune microenvironment. However, the potential mechanism of RA-FLS in regulating the immnue response is not clearly understood. In this study, we demonstrated that the express...

Background: Rheumatoid arthritis is a systemic inflammatory disease with unknown etiology. There has been considerable debate about the relation between thyroid gland and rheumatic diseases.
 Objective: To assessed prevalence of primary hypothyroidism in patients rheumatoid arthritis, as well association severity arthritis.
 Patients Methods: This study cross-sectional observational i...

Brooks et al. [51] RA (8) At 100 mg/kg of cyclophosphamide, 4/4 relapsed at 200 mg/kg and 3/4 improved (2 at 6 months). McSweeney et al. [49] Scleroderma (5) No progression; improved skin scores; one death early post-transplant. Wulffraat et al. [50] JRA (5) All improved. Huhn et al. [54] ITP (4) One patient steroid refractory despite transplant; one steroid independent after transplant. Burt e...

medical treatises around 400 yr B.C.; at that time ‘gout’ was used to describe all types of arthritis. However, the first description of rheumatoid arthritis in the medical literature is generally accorded to Augustin Jacob Landré-Beauvais in 1800 who described rheumatoid arthritis (RA) as ‘asthenic gout’ which exhibits several distinctive features, including predominance in women, a chronic co...