A case is reported of primary late-onset hypogammaglobulinaemia associated with a chronic seronegative, nonerosive arthritis, which was complicated by an episode of septic arthritis due to Mycoplasma pneumoniae. The patient had subcutaneous nodules which have not been regarded previously as a feature of the chronic arthritis associated with hypogammaglobulinaemia. The diagnosis of septic arthri...

We conducted a study to determine the prevalence of extraarticular manifestations (ExRA) in a cohort of predominantly Hispanic and Asian patients with rheumatoid arthritis (RA), to identify factors associated with the development of ExRA, and to compare the prevalence of ExRA between Hispanic and Asian patients. Patients with RA followed in the outpatient rheumatology clinics of a public hospit...

sister mary joseph nodule or sister mary joseph sign refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen. a rare case of sister mary joseph nodule, manifesting as ascites, cachexia and bleeding per rectum, is presented without any primary tumor despite extensive search for the same. normal 0 false false false microsofti...

OBJECTIVES (1) To analyse the in situ expression of adhesion molecules in rheumatoid nodules. (2) To compare the endothelial expression of adhesion molecules in synovial tissue and subcutaneous nodules obtained from the same patients. (3) To compare the expression of adhesion molecules and activation markers on T cell lines from nodules and synovium. METHODS (1) Immunohistochemical analysis b...

The amino acid hydroxyproline constitutes approximately 13 per cent of collagen (1, 2), and 1 to 2 per cent of elastin (2). It is present in no other protein of the body. For this reason, the determination of hydroxyproline has been utilized for the estimation of collagen in various animal tissues (3), and in the fibrinoid material of the subcutaneous nodule of rheumatoid arthritis (4). It is, ...

The classical descriptions of the pathology of rheumatoid arthritis have largely come from autopsy studies in far advanced disease. The frequent use of surgery in recent years has stimulated much interest in the synovial changes by providing material from the earliest proliferative stages. Features previously unrecognized, such as a "distinctive" synovial giant cell, have been described in sero...

A 57 year old gentleman presented with multiple nodular swellings over dorsal aspects of hands (Figure 1), forearms (Figure 2), posterior superior iliac spine and over back (Figure 2) for last two weeks. He was diagnosed with seropositive rheumatoid arthritis (rA) 6 months back and was put on weekly subcutaneous methotrexate (MTX) and oral sulphasalazine. The patient did not notice any nodule d...

BACKGROUND AND PURPOSE No study has previously examined the feasibility of using EA to remove any peripherally located, solid components remaining after treatment of benign solid thyroid nodules by RFA. The aim of this study was to assess the efficacy of EA in removing remnant solid components following the incomplete ablation of benign solid thyroid nodules by RFA. MATERIALS AND METHODS Duri...

©2015 8872147 Canada Inc. or its licensors CMAJ, July 14, 2015, 187(10) E327 A 52-year-old woman with a seven-year history of seropositive rheumatoid arthritis treated with oral prednisolone (5 mg/d) and methotrexate (6 mg/wk) presented after two weeks of experiencing rapidly increasing tender eruptions on her fingers. Clinical examination showed multiple skin-coloured hard nodules of up to 15 ...

to evaluate symbiotic effectiveness and salt tolerance of sinorhizobium meliloti strains, 50 rhizobial strains were isolated from root nodules of medicago sativa cultivated in tehran and zanjan fields. under n-free conditions, the symbiotic effectiveness of different sinorhizobium meliloti strains of bami cultivar were evaluated under greenhouse conditions using 50 sinorhizobium meliloti strain...