The gene transactivation function of nuclear EGFR (nEGFR) has been studied by investigating the genomic co-occupancies of nEGFR and RNA Polymerase II (RNAPII). However, due to RNAPII pausing, the co-recruitment of RNAPII and nEGFR does not necessarily represent productive transactivation. In this study, we integrated gatekeepers of productive transcriptional elongation such as Integrator and Su...

Canonical Wnt signaling plays an essential role in proper craniofacial morphogenesis, at least partially due to regulation of various aspects cranial neural crest development. In effort gain insight into the etiology abnormalities resulting from and/or dysfunction, we sought identify Wnt-responsive targets during chick To this end, leveraged overexpression a canonical antagonist, Draxin, conjun...

Fuzzy logic (FL) and neural network (NNs) methods are commonly applied in a variety of areas the petroleum industry. The area hydrocarbon exploration has seen greatest advancement soft-computing technologies including FL, NNs. In this study, FL NNs have been to log data from Chanda Oil Field, northwest Pakistan, for porosity (PHIT) prediction. input dataset study included four known logs, gamma...