Among the different thyroid carcinomas, papillary carcinoma (PTC) is the most common malignant tumor of the thyroid gland, as well as the most common malignancy among all cancers of the endocrine glands. It is a cancer which among other cancers is characterized by clearly defined rules of diagnosis, treatment and monitoring (follow-up). One of the most important features of PTC is its slow grow...

Objectives: I-131 is a widely used radiopharmaceutical for the management of patients with differentiated thyroid carcinoma (DTC). It is the main agent for the ablation of residual thyroid tissue and the treatment of recurrent or metastatic DTC. However, diagnostic doses of I-131 may cause some form of cell damage “stunning” which reduce subsequent uptake of the therapeutic dose of I-131. In co...

UNLABELLED In 30-50% of patients with metastatic non-medullary thyroid cancer the metastases are not radioiodine-avid and so there is no effective treatment. Retinoids have demonstrated inhibition of thyroid tumor growth and induction of radioiodine uptake. The aim of our study was to assess benefits of the retinoic acid (RA) treatment to re-differentiate non-functional NMTC metastases. PATIE...

To evaluate the outcome of differentiated thyroid cancer (DTC) patients with biochemical persistence of disease (BP) after initial treatment (total thyroidectomy with or without lymph node dissection (LND) and thyroid remnant ablation). BP was defined as suppressed thyroglobulin (Tg) levels <1 ng/ml and rhTSH-stimulated thyroglobulin (St-Tg) >1ng/ml, with no evidence of structural disease. Stru...

The thyroid consists of two lobes that are connected by an isthmus. It is located anterior to the trachea between the cricoid cartilage and the suprasternal notch. It produces two related hormones, thyroxine (T4) and triiodothyronine (T3). Benign nodules and thyroid cancer are relatively common and amenable to detection by physical examination. Nuclear medicine is a part of medicine that uses r...

The authors of the recently published ‘‘Radiation Safety in the Treatment of Patients with Thyroid Diseases by Radioiodine (I): Practice Recommendations of the American Thyroid Association’’ (1) are to be commended for creating a document that reflects the result of countless hours of literature review, survey compilation, discussion, and compromise. This study has systematically applied techni...

Among the different thyroid carcinomas, papillary carcinoma (PTC) is the most common malignant tumor of the thyroid gland, as well as the most common malignancy among all cancers of the endocrine glands. It is a cancer which among other cancers is characterized by clearly defined rules of diagnosis, treatment and monitoring (follow-up). One of the most important features of PTC is its slow grow...

Introduction: The treatment and particularly the extension of surgical therapy of papillary thyroid carcinoma (PTC) remain still controversial in some issues, especially for the lack of preoperative information or variables that allow predicting the level of aggressiveness of the tumor. Aim of the study: The purpose of the study was to assess the impact of the central node neck dissection (CNND...