In this paper, we present a novel packaging architecture for Optoelectronic Multi-Chip-Modules (OEMCM) based on fiber image guides. Fiber image guides (FIGs) are densely packed lattices of small core fibers that have been traditionally used in medical endoscopes and other remote inspection devices. In our chip packaging architecture, small, rigid segments of FIGs are used to fabricate 3D optica...

Breast cancer is the most common type of cancer and the fifth leading cause of death in women over 40. Therefore, prompt diagnostic and treatment is essential. In this work a TMA Computer Aided Diagnosis (CAD) system has been implemented to provide support to pathologists in their daily work. For that purpose, the tool covers each and every process from the TMA core image acquisition to their i...

infection with hepatitis c virus (hcv) is a worldwide problem. among hcv proteins, core antigen (ag), besides its importance for diagnostic application is a prime candidate for component of a vaccine. herein, we report results of studies on production of the hydrophilic domain of core ag (2-122) in native conformation by an arabinose induction system in e.coli and the primary characterization o...

We present a model of the Cassini state Mercury that comprises an inner core, fluid and mantle. Our includes inertial gravitational torques between interior regions, viscous electromagnetic (EM) coupling at boundaries core. show Mercury's regions is sufficiently strong obliquity mantle spin axis deviates from rigid planet by no more than 0.01 arcmin. The decreases with increasing core size, but...

Diacylglycerol lactones built with a rigid 4-[(methylphenyl)ethynyl]phenyl rod that is separated from the exocyclic acylcarbonyl of the DAG-lactone core by a spacer unit of variable length were synthesized and studied. Binding affinities for a panel of classical and novel PKC isozymes in two different phospholipid environments, one corresponding to the plasma membrane of cells, were determined....

An unexpected and previously unknown resorcinarene mono-crown with a fused benzofuran moiety in its macrocyclic core was obtained as a byproduct from a bridging reaction of tetramethoxy resorcinarene with tetraethylene glycol ditosylate. The formation of the fused benzofuran moiety in the resorcinarene macrocycle resulted in a unique rigid and puckered boat conformation, as shown by XRD studies...

Matching 3D rigid point clouds in complex environments robustly and accurately is still a core technique used in many applications. This paper proposes a new architecture combining error estimation from sample covariances and dual global probability alignment based on the convolution of adaptive Gaussian Mixture Models (GMM) from point clouds. Firstly, a novel adaptive GMM is defined using prob...

We have used I5N NMR relaxation experiments to probe, for the glycosylated human CD2 adhesion domain, the overall molecular motion, as well as very fast nanosecond-picosecond (ns-ps) and slow millisecond-microsecond (ms-ps) internal motions. Using a novel analysis method that considers all residues, we obtained a correlation time for the overall motion of 9.5 + 0.3 ns. Surprisingly, we found a ...